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TranscriptomicsSmall Marine Neurotoxin Elicits Common Antibody Response in Zebrafish and Sea Lions
The neurotoxic amino acid, domoic acid, is naturally produced by marine phytoplankton and presents a significant health threat to marine mammal and human populations. Currently, diagnostic tools to assess exposure are not available, yet concerns regarding health impacts associated with low-level re...
ORGANISM(S): Danio rerio 
2013-01-03 | E-GEOD-34716 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcription analysis of Escherichia coli in response to extremely low-frequency magnetic fields
The widespread use of electricity raises the question of whether or not 50 Hz (power line frequency in Europe) magnetic fields (MFs) affect organisms. We investigated the transcription of Escherichia coli K-12 MG1655 in response to extremely low-frequency (ELF) MFs. Fields generated by three signal ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-01-28 | E-GEOD-35371 | biostudies-arrayexpress
UnknownRole of auditory feedback for vocal production learning in the Egyptian fruit bat.
Not available
S-EPMC11493346 | biostudies-literature
UnknownArtificial intelligence-guided design of lipid nanoparticles for pulmonary gene therapy.
Not available
S-EPMC12149338 | biostudies-literature
UnknownCarboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity.
Not available
S-EPMC11046700 | biostudies-literature
ProteomicsArabidopsis thaliana polyQ - interactors
We've demonstrated that plants are resistant to the overexpression of polyglutamine (polyQ) extended proteins that cause protein aggregation and Huntington's disease in human cells. To investigate which proteins, maintain polyQ proteins correctly folded and avoid polyQ aggregates in plant cells. Ou...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-07-17 | PXD041001 | Pride
Arabidopsis thaliana Polyq-extended proteins Huntington's disease 
ProteomicsIn planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation
LiP-MS experiment was performed HEK293 cells which are expressing eGFP +mRFP-HTTQ74 or eGFP-SPP+mRFP-HTTQ74 to analyze structural changes in proteome level between these two conditions.
ORGANISM(S): Homo sapiens (Human) 
2023-08-11 | PXD044409 | Pride
Arabidopsis thaliana Huntington’s disease Protein aggregation Caenorhabditis elegans 
ProteomicsIn planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation.
We overexpressed eGFP, eGFP-SPP and pmRFP-Q74 construct in HEK93 cells. We made immunoprecipitation of GFP. We compare the interactome of eGFP and eGFP-SPP.
ORGANISM(S): Homo sapiens (Human) 
2023-08-11 | PXD044408 | Pride
Huntington’s disease Arabidopsis thaliana Protein aggregation 
ProteomicsIn planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation.
We have Q67 worms with overexpression of SPP construct or without overexpression of SPP construct. We compare whole proteome from control group with worms overexpressing of SPP construct
ORGANISM(S): Caenorhabditis elegans 
2023-08-11 | PXD044145 | Pride
Huntington’s disease Arabidopsis thaliana Protein aggregation Caenorhabditis elegans 
UnknownMicrobiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Not available
S-EPMC5786503 | biostudies-literature
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