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ProteomicsMapping of the hSOX10 protein interactome in human melanoma
The transcription factor SOX10 is a central regulator of melanoma biology, influencing tumor initiation, progression, phenotypic plasticity, and therapeutic resistance. However, the molecular mechanisms underlying these diverse functions remain incompletely understood. To elucidate the protein-prote...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD067868 | Pride
Interactome mapping Mass spectrometry Miniturbo Melanoma Proximity-based biotinylation Protein-protein interactions Hsox10 
ProteomicsSCFCyclin F targets the metabolic protein Sirtuin 5 for ubiquitination
Cell cycle transitions are regulated by a number of coordinating signaling events. The ubiquitin-proteasome system is an important part of this cell cycle signaling. Cyclin F, a substrate adapter for the SCF (SKP1/CUL1/F-box) E3 ubiquitin ligase, is an important regulator of cell cycle progression. ...
ORGANISM(S): Homo Sapiens (human) 
2020-11-17 | PXD019396 | JPOST Repository
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