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TranscriptomicsPhylogenetic & expression analysis of the bHLH transcription factor family: genomic approach to cellular differentiation
A phylogenetic analysis of seven different species (human, mouse, rat, worm, fly, yeast, and plant) utilizing all (541) basic helix-loop-helix (bHLH) genes identified, including expressed sequence tags (EST), was performed. A super-tree involving six clades and a structural categorization involving ...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20259 | biostudies-arrayexpress
TranscriptomicsE-cadherin and EMT regulation by bHLH factors: a new role for the class I gene E2-2 (TCF4) and its comparison with E47.
Loss of expression of the cell-cell adhesion molecule E-cadherin is an essential event for epithelial-mesenchymal transition (EMT), a process that allows cell migration in the developing embryo and during tumour invasion. Transcriptional repression has emerged as the main mechanism responsible for E...
ORGANISM(S): Canis lupus familiaris 
2010-06-24 | E-GEOD-9145 | biostudies-arrayexpress
Genomics959 Sequences of bHLH genes
CDS Sequences of bHLH genes
PRJEB36432 | ENA
GenomicsA basic helix-loop-helix transcription factors network mediates the brassinosteroid signal [ChIP-seq]
To investigate the genome-wide occupancies of INCREASED LEAF INCLINATION1 (ILI1)-BINDING bHLH-1 (IBH1) (At2g43060), IBH1 ChIP analysis followed by direct sequencing (ChIP-Seq) on the p35S::IBH1-GFP (IBH1OE) line and a control line p35S::GFP (GFP OE) were conducted. Antibodies against GFP in the GFP...
ORGANISM(S): Arabidopsis thaliana 
2014-03-05 | E-GEOD-51120 | biostudies-arrayexpress
GenomicsTranscriptional profiling of Schistosoma mansoni after amputation under sustained bHLH RNAi
Transcriptional profiling of Schistosoma mansoni after amputation under sustained bHLH RNAi
PRJNA1499799 | ENA
TranscriptomicsA triple-HLH/bHLH Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways
The environmental and endogenous signals, light, temperature, brassinosteroid (BR), and gibberellin (GA), regulate cell elongation largely by controlling the expression of the PRE family helix-Loop-helix (HLH) factors, which promote cell elongation by interacting antagonistically with another HLH fa...
ORGANISM(S): Arabidopsis thaliana 
2015-01-01 | E-GEOD-41766 | biostudies-arrayexpress
ProteomicsCo-Immunoprecipitation of transcriptional regulators of stomatal development in B. distachyon
Stomata are pores in the epidermis of plants that can open and close and allow for gas exchange vital for photosynthesis and regulate transpiration. Stomatal development is driven by a set of conserved bHLH transcription factors (SPCH, MUTE, FAMA, and their heterodimerization partners ICE1, SCRM2), ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-03-11 | PXD035582 | Pride
Stomatal development Bhlh transcription factor Co-immunoprecipitation Brachypodium distachyon Interaction partners Lc-ms/ms 
TranscriptomicsA basic helix-loop-helix transcription factors network mediates the brassinosteroid signal [RNA-seq]
To understand how atypical bHLH, INCREASED LEAF INCLINATION1 (ILI1)-BINDING bHLH-1 (IBH1) (At2g43060), and close homologue, IBH1-like1 (IBL1) (At4g30410), interact to regulate cell elongation, genome-wide RNA-Seq expression analyses of IBH1 and IBL1 gain-(IBH1OE, IBL1OE) and loss-of-function (ibh1 (...
ORGANISM(S): Arabidopsis thaliana 
2014-03-05 | E-GEOD-51119 | biostudies-arrayexpress
GenomicsDNA binding specificity for the bHLH-PAS transcription factor family
DNA binding specificity for the bHLH-PAS transcription factor family
PRJNA671496 | ENA
ProteomicsbHLH Transcription Factors that Facilitate K+ Uptake During Stomatal Opening are Repressed by Abscisic Acid through Phosphorylation
Stomata open in response to light and close following exposure to abscisic acid (ABA). They regulate gas exchange between plants and atmosphere, allowing plants to adapt to changing environmental conditions. ABA binding to receptors initiates a signaling cascade that involves protein phosphorylation...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2013-06-28 | PXD000235 | Pride
Arabidopsis Stomatal guard cells Ltq 
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