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Puchalka2008 - Genome-scale metabolic network of Pseudomonas putida (iJP815) This model is described in the article: Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology. Puchałka J, Oberhardt MA,...
2015-07-30 | MODEL1507180044 | BioModels
We analyzed a deletion mutant of the ECF M-OM-^C factor SigX and applied mRNA profiling to define the SigX dependent regulon in P. aeruginosa in response to low osmolarity medium conditions. Furthermore, the combination of transcriptional data with chromatin immunoprecipitation (ChIP) followed by hi...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
The opportunistic bacterium Pseudomonas aeruginosa is a major nosocomial pathogen causing both devastating acute and chronic persistent infections. During the course of an infection, P. aeruginosa rapidly adapts to the specific conditions within the host. In the present study, we aimed at the identi...
ORGANISM(S): Pseudomonas aeruginosa 
Resistance to tyrosine kinase inhibitors is an essential issue concerning targeted therapy in renal cancer. This research focuses on molecular background of resistance to axitinib and sorafenib observed from the very beginning of a standard two-dimensional cell culture in monolayer as well as in thr...
ORGANISM(S): Homo sapiens (Human) 
2018-01-02 | PXD002600 | Pride
Recombinant attenuated Salmonella are believed to act as powerful live vaccine carrier able to elicit protection against many infectious agents. ∆aroA exhibits auxotrophy for aromatic amino acids and is commonly used for attenuation. Interestingly, deletion of aroA dramatically increased virulence...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
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