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BACKGROUND: Young age at portoenterostomy has been linked to improved outcome in biliary atresia, but pre-existing biological factors may influence the rate of disease progression. In this study, we aimed to determine whether molecular profiling of the liver identifies stages of disease at diagnosis...
ORGANISM(S): Homo sapiens 
Normothermic machine perfusion (NMP) after static cold storage is increasingly used for preservation and assessment of human donor livers prior to transplantation. Biliary viability assessment during NMP reduces the risk of post-transplant biliary complications. However, understanding molecular cha...
ORGANISM(S): Homo sapiens 
Mapping Disease Pathways for Biliary Atresia
Mapping Disease Pathways for Biliary Atresia
Biliary complications are disabling conditions that arise in up to 25% of liver transplanted patients, resulting in additional surgical procedures, re-transplantation or, in the absence of a suitable regraft, death. Here, we investigate the role of the primary cilia, a highly-specialised sensory org...
ORGANISM(S): Homo sapiens 
2024-07-12 | GSE220720 | GEO
Biliary complications are disabling conditions that arise in up to 25% of liver transplanted patients, resulting in additional surgical procedures, re-transplantation or, in the absence of a suitable regraft, death. Here, we investigate the role of the primary cilia, a highly-specialised sensory org...
ORGANISM(S): Mus musculus 
2024-07-12 | GSE220820 | GEO
Real time quantitative PCR analysis of human biliary epithelial cells
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