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ProteomicsProteomic analysis of HepG2 cells after mutated ß-catenin depletion
ß-catenin is a main oncogene in a large number of cancers (colorectal, liver, melanoma, uterus). Local immunosuppression induced by certain cancers remains a major problem of resistance to immunotherapies and its molecular mechanism remains poorly understood. Recently, ß-catenin mutated tumors (hepa...
ORGANISM(S): Homo sapiens (Human) 
2024-07-08 | PXD043841 | Pride
Hepatocellular carcinoma Quantitative proteome Liver Hepatoblastoma Mutated ß-catenin 
TranscriptomicsSmall RNA seq of HepG2 cells expressing shRNA targeting wild-type, mutated or both ß-catenin versus shRNA control
HepG2 cells expressing doxycycline-inducible shRNA were treated by doxycycline for 7 days. Four stable cell lines were used: HepG2 cells expressing a control shRNA; HepG2 cells expressing a shRNA targeting wild-type ß-catenin ; HepG2 cells expressing a shRNA targeting mutated ß-catenin ; HepG2 cell...
ORGANISM(S): Homo sapiens 
2026-09-03 | E-MTAB-15638 | biostudies-arrayexpress
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