Hepatoblastoma - OmicsDI

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Transcriptomics (846)
Unknown (461)
Genomics (178)
Proteomics (27)
Metabolomics (9)
Other (3)
Clinical (2)
Methylation profiling (2)
Models (1)
Genomic (1)

Organisms

Homo sapiens (661)
Mus musculus (208)
Rattus norvegicus (23)
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Hepatitis B virus (8)
Human betaherpesvirus 5 (8)
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Japanese encephalitis virus group (8)
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Marmota monax (7)
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synthetic construct (3)
Aspergillus flavus (1)
Mus musculus musculus x Mus musculus domesticus (1)
Bacillus cereus ATCC 14579 (1)
Plasmodium berghei (1)
Oncorhynchus mykiss (1)
Escherichia coli (1)
Gallus gallus (1)
Rattus rattus (1)

Organisms

Homo sapiens (85)
Mus musculus (17)
Microbiota (1)

Repository

biostudies-arrayexpress (801)
ENA (124)
geo (90)
EGA (14)
MassIVE (13)
MetaboLights (9)
pride (8)
iProX (5)
jPOST (2)
ExpressionAtlas (1)
Cell Collective (1)
dbGaP (1)

Tissue

Hepatocyte (5)
Cell culture (2)
HepG2 cell (1)
Liver (1)

Disease

Oral squamous cell carcinoma (1)
Endometrium adenocarcinoma (1)
Gastric tubular adenocarcinoma (1)
Undifferentiated carcinoma (1)
Amelanotic melanoma (1)
Salivary gland squamous cell carcinoma (1)
Endometrial endometrioid adenocarcinoma, variant with squamous differentiation (1)
Ovarian endometrioid adenocarcinoma (1)
Gliosarcoma (1)
B-cell prolymphocytic leukemia (1)
Childhood acute monocytic leukemia (1)
Mucinous gastric adenocarcinoma (1)
Hereditary thyroid gland medullary carcinoma (1)
Extrarenal rhabdoid tumor (1)
Meningioma (1)
Leiomyoma, epithelioid (1)
Primary effusion lymphoma (1)
Cecum adenocarcinoma (1)
Bronchioloalveolar carcinoma (1)
Adenosquamous lung carcinoma (1)
Pancreatic adenosquamous carcinoma (1)
Laryngeal squamous cell carcinoma (1)
Duodenal adenocarcinoma (1)
Adult B acute lymphoblastic leukemia (1)
Uterine leiomyosarcoma (1)
Endometrial stromal sarcoma (1)
Chronic eosinophilic leukemia (1)
Ampulla of Vater adenocarcinoma (1)
Cutaneous melanoma (1)
Colon carcinoma (1)

Technology Type

Mass Spectrometry (8)
Mass spectrometry assay (6)
Shotgun proteomics (5)
Mass spectrometry (3)
Data-independent acquisition (2)
Bottom-up proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (16)
Illumina NovaSeq 6000 (9)
Illumina HiSeq 2000 (6)
Illumina NovaSeq X (4)
NextSeq 550 (4)
Q Exactive (4)
Illumina HiSeq 4000 (3)
Illumina MiSeq (2)
Using NEBNext Ultra II DNA Library (1)
Illumina TrueSeq Exome Kit (1)
Qiagen DNAeasy blood and tissue kit (1)
Illumina Human-12 v1 Expreesion BeadChip (1)
Heraeus SEPATECH (1)
Nucleospin® Extract II (1)
Qubit (1)
Hybridization Chamber, stainless,Hybridization oven rotator (1)
Flow Cytometry (1)
Illumina bead array Reader confocal scanner (1)
Unspecified (1)
Axon- GenePix4000B (1)
- (1)
Ion Torrent Proton (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
Illumina HiSeq 1500 (1)
6520A Quadrupole Time-of-Flight LC/MS (1)
LTQ Orbitrap (1)
LTQ Orbitrap Elite (1)
LTQ XL ETD (1)
Orbitrap Astral (1)

Publication Date

2014 (117)
2013 (116)
2015 (113)
2012 (94)
2011 (77)
2010 (75)
2016 (71)
2008 (36)
2025 (27)
2009 (25)
2026 (22)
2020 (19)
2007 (19)
2021 (18)
2017 (18)
2024 (16)
2023 (16)
2022 (15)
2018 (12)
2019 (9)
2005 (6)
2004 (2)
2006 (1)
2003 (1)
2027 (1)

CHEBI ID

CHEBI:22660 (1)
CHEBI:16857 (1)
CHEBI:18237 (1)
CHEBI:17148 (1)
CHEBI:17822 (1)
CHEBI:15428 (1)
CHEBI:15356 (1)
CHEBI:16449 (1)
CHEBI:27266 (1)
CHEBI:28044 (1)
CHEBI:15824 (1)
CHEBI:25017 (1)
CHEBI:6650 (1)
CHEBI:18257 (1)
CHEBI:15891 (1)
CHEBI:16335 (1)
CHEBI:28300 (1)
CHEBI:25094 (1)
CHEBI:7916 (1)
CHEBI:18186 (1)
CHEBI:28842 (1)
CHEBI:16027 (1)
CHEBI:16708 (1)
CHEBI:15741 (1)
CHEBI:16196 (1)
CHEBI:27897 (1)
CHEBI:17191 (1)
CHEBI:15756 (1)
CHEBI:17368 (1)
CHEBI:30769 (1)

Metabolite Name

O-Acetylserine (2)
L-Arginine (2)
Taurine (2)
[(2S,3R,4S,5S)-3-[(2S,3R,4R,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl] (4aS,6aS,6bR,10S,12aR,14bS)-10-[(2R,3R,4S,5S,6R)-4-hydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate_30.2% (1)
NCGC00025125-21!N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide [IIN-based on: CCMSLIB00000845970] (1)
NCGC00380698-01_C24H30O13_Cyclopenta[c]pyran-4-carboxylic acid, 1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a-hydroxy-7-methyl-5-oxo-, 2-(3,4-dihydroxyphenyl)ethyl ester, (1S,4aR,7aR)- (1)
2-[4-[(3S,3aR,6S,6aR)-6-[3-methoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol (1)
(G)(NAM)-AemA;(3s-4)-(G)(NAM)-AemA (1)
MMV676480 (1)
Flavone base + 3O, 2MeO, O-guaiacylglyceryl-Hex (1)
NCGC00347420-02_C39H65NO12_15-Hydroxyspirosolan-3-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside (1)
NCGC00381337-01_C64H104O30_Pentopyranosyl-(1->4)pentopyranosyl-(1->4)-1-O-[(3beta,5xi,9xi,18xi)-3-{[hexopyranosyl-(1->3)hexopyranosyl-(1->4)-6-deoxyhexopyranosyl]oxy}-28-oxoolean-12-en-28-yl]hexopyranose (1)
(7S,9E,11S,12R,13S,14S,15S,16R,17S,18S,19E,21Z)-26-{4-[(furan-2-yl)carbonyl]piperazin-1-yl}-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1,3,5(28),9,19,2... (1)
NCGC00380818-01_C17H15ClO6_7-Chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-3,4'-dione (1)
MGDG (18:3/18:4)_(2S)-1-O-(9Z,12Z,15Z-octadecatrienoyl)-2-O-(6Z,9Z,12Z,15Z-octa-decatetranoyl)-3-beta-D-galacto-pyranosyl-sn-glycerol (1)
(NAG)(NAM)-AeKA[3-NH2-GGGG] (1)
NCGC00347534-02![2-[4-hydroxy-2,5-bis(hydroxymethyl)-3-(2-methylpropanoyloxy)oxolan-2-yl]oxy-6-(hydroxymethyl)-4,5-bis(2-methylpropanoyloxy)oxan-3-yl] decanoate [IIN-based on: CCMSLIB00000848581] (1)
Methyl 2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methylbenzoyl)-3,5-dihydroxybenzoate (1)
Pesticide3_Chlorfluazuron_C20H9Cl3F5N3O3_Benzamide, N-[[[3,5-dichloro-4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]amino]carbonyl]-2,6-difluoro- (1)
NCGC00384992-01_C20H26O6_ (1)
(NAG)(NAM)-AemAG;(3s-4)-(G)(NAM)-AemA (1)
Solanidine base + O-Hex-Hex (1)
(2S,3R,4S,5R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,6S,8R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol (1)
NCGC00380130-01_C15H26O4_1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1,4-dihydroxy-5,5,8a-trimethyl- (1)
NCGC00169037-02_C25H34O8_beta-D-Glucopyranoside, 5-(4-hydroxyphenyl)-1-[2-(4-hydroxyphenyl)ethyl]pentyl (1)
NCGC00347542-02!4-[5-(3,4-dimethoxyphenyl)-3,4-dimethyloxolan-2-yl]phenol [IIN-based on: CCMSLIB00000848919] (1)
Cyclopamine (1)
NCGC00381245-01_C22H30O8_2-[6-{[(2Z)-4-Acetoxy-2-methyl-2-butenoyl]oxy}-2-hydroxy-3-(3-hydroxy-1-propen-2-yl)-4-methyl-4-vinylcyclohexyl]acrylic acid (1)
(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-((3-(benzo[d][1,3]dioxol-5-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (1)
(3?,5?,9?,16?,18?,22?)-22-Acetoxy-16-hydroxy-13,28-epoxyoleanan-3-yl 6-deoxy-?-L-mannopyranosyl-(1->2)-?-D-galactopyranosyl-(1->3)-[?-D-glucopyranosyl-(1->2)]-?-D-glucopyran osiduronic acid_major (1)

First Public Date

2025 (16)
2023 (15)
2021 (13)
2026 (12)
2020 (10)
2015 (10)
2014 (10)
2024 (9)
2022 (9)
2017 (7)
2018 (5)
2019 (4)
2016 (2)
2013 (2)

Study status

Active, not recruiting (1)
Recruiting (1)

Study type

Transcription profiling by array (572)
RNA-seq of coding RNA (52)
Comparative genomic hybridization by array (34)
Methylation profiling by array (33)
ChIP-seq (16)
Unknown experiment type (11)
RNA-seq of total RNA (11)
RNA-seq of non coding RNA (11)
ChIP-chip by tiling array (9)
Genotyping by array (9)
Methylation profiling by high throughput sequencing (5)
Transcription profiling by RT-PCR (4)
Other (4)
DNA-seq (4)
MicroRNA profiling by array (3)
Human - High-throughput sequencing (2)
High-throughput sequencing (2)
Human - One-color microarray (2)
RNAi profiling by array (2)
ChIP-chip by array (2)
Transcription profiling by SAGE (1)
Human - Two-color microarray (1)
Animal - One-color microarray (1)
MicroRNA profiling by high-throughput sequencing (1)
One-color microarray (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
MicroRNA profiling by high throughput sequencing (1)
ATAC-seq (1)
RIP-seq (1)

Release Date

2014 (128)
2013 (120)
2015 (118)
2012 (98)
2016 (84)
2010 (76)
2011 (75)
2022 (67)
2024 (62)
2025 (58)
2021 (52)
2023 (51)
2020 (48)
2019 (45)
2008 (38)
2017 (37)
2009 (27)
2018 (24)
2007 (23)
2026 (16)
2005 (8)
2004 (3)
2006 (2)
2003 (1)
2002 (1)

Lab affiliation

Center of Excellence in Systems Biology, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand (1)
Chulalongkorn University Systems Bilogy center, Research affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (1)
Division Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Germany (1)
Lab of proteoforms' interactomics, Institute of Biomedical Chemistry, Moscow, Russia (lab head) (1)
Merck Healthcare KGaA (1)
Peter MacCallum Cancer Centre, Australia (1)
Univ. Bordeaux, INSERM, BRIC, U1312, Bordeaux, France (1)
Univ. Bordeaux, Inserm, BMGIC, U1035, 33076 Bordeaux, France. (1)

Location

Netherlands (1)
United States (1)

Keyword

SEER (1)
Gastrointestinal (1)
Malignant (1)
Pediatric (1)

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Exploring the Effects and Mechanisms of Curcumin on Proliferation, Apoptosis, and Oxidative Stress in Hepatoblastoma cell line via the TLR4/TRAF6/MAPKs Pathway

A combination of bioinformatics and network pharmacology was used to screen curcumin's target genes and related signaling pathways in treating hepatocellular carcinoma. Curcumin-Containing Serum（CUR） was prepared. Cisplatin(CDDP) served as the positive control .The CCK-8 assay, scratch assay, and...

2025-11-28 | MTBLS13412 | MetaboLights

Transcription profiling of human hepatoblastoma identifies a 16 gene signature for invasive and metastatic blastomas

Hepatoblastoma, the most common pediatric liver cancer, is tightly linked to excessive Wnt/�-catenin signaling. Microarray analysis identified two tumor subclasses resembling distinct phases of liver development, and a 16-gene signature discriminated invasive and metastatic hepatoblastomas, and pred...

ORGANISM(S): Homo sapiens

2009-07-01 | E-MEXP-1851 | biostudies-arrayexpress

Genome-wide analysis of long noncoding RNA (lncRNA) expression in hepatoblastoma tissues

We performed a genome-wide analysis of lncRNA expression in hepatoblastoma tissues to identify novel targets for further study of hepatoblastoma.We found that 2736 lncRNAs were differentially expressed in hepatoblastoma tissues. The genome-wide analysis of lncRNA expression in these tissues was perf...

ORGANISM(S): Homo sapiens

2013-12-31 | E-GEOD-51701 | biostudies-arrayexpress

Volasertib preclinical activity in high-risk hepatoblastoma

Relapsed and metastatic hepatoblastoma represents an unmet clinical need with limited chemotherapy treatment options. In a chemical screen, we identified volasertib as an agent with in vitro activity, inhibiting hepatoblastoma cell growth while sparing normal hepatocytes. Volasertib targets PLK1 and...

EGAS00001004827 | EGA

PAGE4, upregulated in a novel iPSC-derived hepatoblastoma model, promotes hepatoblastoma progression

PRJNA1261914 | ENA

An integrated molecular study of 20 hepatoblastoma pairs using whole genome sequencing and RNA sequencing

Hepatoblastoma is an uncommon malignant liver cancer occurring in infants and children. The mutant background of hepatoblastoma has not been fully demonstrated. The aim of this study is to genomically depict the mutational landscape of hepatoblastoma through an integrative analysis of whole genome s...

EGAS00001002772 | EGA

Proteomics of hepatoblastoma and NAT samples

Proteomics of hepatoblastoma, normal liver tissues and NAT samples before or after chemotherapy.

ORGANISM(S): Homo Sapiens

2024-11-13 | PXD057828 |

Strategy for High-Risk and Treatment-Refractory Hepatoblastoma

Hepatoblastoma Study

PRJEB64605 | ENA

Expression data from hepatoblastoma tissues

PRJNA543290 | ENA

Comparative genomic hybridization of human hepatoblastomas identifies two tumor subclasses resembling distinct phases of liver development

A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Hepatoblastoma, the most common pediatric liver cancer, is tightly linked to excessive Wnt/C/B?B=-catenin signaling. Microarray analysis identifitwo tumor subclasses resemb...

ORGANISM(S): Homo sapiens

2008-12-19 | E-MEXP-1852 | biostudies-arrayexpress

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