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GenomicsTo examine the role of p300 in the SMARCA4–p53 regulatory axis, we performed ChIP-seq to assess p300, p53, H3K27ac, HDAC1, HDAC2 occupancy in BIN-67 cells
ChIP-seq was performed in BIN-67, BIN-67 p53ko, BIN-67 with SMARCA4 restoration and BIN-67 p53ko cells with SMARCA4 restoration to assess the impact of SMARCA4 and p53 on the pull downs of p300, H3K27ac, p53, HDAC1 and HDAC2.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15700 | biostudies-arrayexpress
GenomicsAssessing SMARCA4 restoration contribution to global changes in p300 occupancy in BIN-67 cells
We aim to test how SMARCA4 restoration impacts p300 occupancy distribution. To this aim we generated ChIP-seq samples in BIN-67 with or without A-485 treatment (1 μM, 24h), as a proxy for p300 acetylatransferase inhibition, and BIN-67 with inducible SMARCA4 restoration (1 μg/ml Doxycycline for 24h)....
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15699 | biostudies-arrayexpress
TranscriptomicsRNA-seq from ENCODE/UW
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Richard Sandstrom mailto:sull@u.washington.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This tra...
ORGANISM(S): Mus musculus 
2012-07-20 | E-GEOD-39524 | biostudies-arrayexpress
TranscriptomicsTranscription analysis of the porcine alveolar macrophage M-oM-
Investigation of whole genome gene expression level changes in porcine alveolar macrophage response to co-infection of PRRSV and M. hyopneumoniae The results in this study will be further described in Bin li et al., 2013. BMC genomics. A 24 chip study using total RNA recovered from four separate gro...
ORGANISM(S): Sus scrofa 
2014-05-30 | E-GEOD-49882 | biostudies-arrayexpress
ProteomicsProjDIA: Fragment-Bin Projection Scoring and Calibrated Confidence for Direct Infusion DIA Proteomics
Direct-infusion shotgun proteome analysis (DI-SPA) increases throughput by removing liquid chromatography, but the resulting DIA spectra are highly multiplexed and difficult to interpret. This dataset was generated to evaluate ProjDIA, a computational workflow for direct-infusion DIA proteomics. Pro...
ORGANISM(S): Homo sapiens (Human) 
2026-04-02 | PXD076477 | Pride
Mcf7 Proteomics Projdia Direct infusion Dia Species entrapment Di-spa Hela Label-free quantification 
UnknownOptimizing e-commerce warehousing through open dimension management in a three-dimensional bin packing system.
Not available
S-EPMC10588690 | biostudies-literature
Transcriptomicsp53-ko rescues gene expression changes mediated by p300 acetyltransferase inhibition
RNA-seq samples in BIN-67 and BIN-67p53-ko cells with or without A-485 treatment (1μM, 24h). The goal of the experiment is to assess the genes that are regulated by p300 acetyltransferase inhibition using A-485 treatment and weather p53-ko can rescue this phenotype.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15706 | biostudies-arrayexpress
TranscriptomicsTranscription analysis of the porcine alveolar macrophage （PAM） response to co-infection of porcine reproductive and respiratory syndrome virus (PRRSV) and M. hyopneumoniae (Mhp)
Investigation of whole genome gene expression level changes in porcine alveolar macrophage response to co-infection of PRRSV and M. hyopneumoniae The results in this study will be further described in Bin li et al., 2013. BMC genomics.
ORGANISM(S): Sus scrofa 
2014-05-30 | GSE49882 | GEO
TranscriptomicsCo-infection wtih porcine reproductive and respiratory syndrome virus (PRRSV) and M. hyopneumoniae (Mhp) enhances pathogenicity by upregulation of inflammatory response in piglets
To investigate the gene expression level changes in the whole genome scale in porcine alveolar macrophage collected from the piglets individually or dually infected with PRRSV and Mph The results in this study will be further described in Bin li et al., 2021. Veterinary microbiology
ORGANISM(S): Sus scrofa 
2021-07-31 | GSE181105 | GEO
UnknownA multi-bin rarefying method for evaluating alpha diversities in TCR sequencing data.
Not available
S-EPMC11246167 | biostudies-literature
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