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MetabolomicsShotgun lipidomics of HeLa whole-cell lysates and lysosomes following LLOMe treatment

Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach, we here identified the bridge-like lipid transport protein VPS13C/PARK23 as a key component of a...

2026-07-03 | MTBLS14737 | MetaboLights
MetabolomicsIdentification of metabolites of trifunctional sphingomyelin (TFSM1) in HeLa 229 cells infected with Chlamydia trachomatis

Chlamydia trachomatis is an obligate intracellular bacterial pathogen and a leading cause of sexually transmitted infections worldwide. During its biphasic developmental cycle, infectious, non-replicative elementary bodies alternate with replicative reticulate bodies within a membrane-bound intra...

2026-08-10 | MTBLS15303 | MetaboLights
MetabolomicsTargeted Sphingolipid analysis of HeLa knockout for expression of GRASP55
Not available
ORGANISM(S): Homo sapiens 
ST001877 | MetabolomicsWorkbench
MetabolomicsUntargeted phospholipid analysis of HeLa silenced for or overexpressing GOLPH3
Not available
ORGANISM(S): Homo sapiens 
ST001674 | MetabolomicsWorkbench
MetabolomicsTargeted Sphingolipid analysis of HeLa silenced for or overexpressing GOLPH3 or LCS
Not available
ORGANISM(S): Homo sapiens 
ST001673 | MetabolomicsWorkbench
TranscriptomicsHost cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis
M. hominis adherence, colonisation and invasion of HeLa cells were characterised in a time-course study using microarray-based analysis of the HeLa cell transcriptome: 0 h to monitor the baseline of transcription, 4 h to examine host reactions to mycoplasma attachment, 48 h to capture in addition th...
ORGANISM(S): Homo sapiens 
2014-02-06 | E-GEOD-54698 | biostudies-arrayexpress
GenomicsHeLa Cell Genome Sequencing Studies

This study contains all authorized whole genome sequence data of the HeLa cell line from datasets currently in dbGaP. These data have been approved for health, medical, and/or biomedical research purposes. Access to these data can be granted for one year. Accessible data will include the studies ...

phs000640.v1.p1 | EGA
MetabolomicsExamination of labeled glucose utilization in central carbon metabolism in HeLa cells post WNT stimulation
Not available
ORGANISM(S): Homo sapiens 
ST001320 | MetabolomicsWorkbench
TranscriptomicsHeLa E2F1 ChIP-chip experiments
These are three biological replicates. HeLa cells were crosslinked on separate days. In each case, a matched total from the same crosslinking was produced in parallel. Amplicons were made from each and hybridized onto ENCODE region tiling arrays. Two color arrays were used; ChIP was red, Total was g...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4306 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profile in Newcastle disease virus-infected HeLa cells
Three small RNA libraries constructed from uninfected HeLa cells or the cells infected with NDV strain Herts/33 at 6 and 12 hr post inoculation were sequenced using an Illumina platform.Three replicates of each group (Mock, NDV-6h and NDV-12h) were prepared and pooled separately for library construc...
ORGANISM(S): Homo sapiens 
2020-11-08 | E-MTAB-9690 | biostudies-arrayexpress
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