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TranscriptomicsCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeostasis in response to oxidative stress by the regulation of multiple cytoprotective genes. Without stressors the activity of Nrf2 is inhibited by its interaction with the kelch-like ECH-associated protei...
ORGANISM(S): Mus musculus 
2015-10-31 | E-GEOD-71695 | biostudies-arrayexpress
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
UnknownAsphalt Binder "Skincare"? Aging Evaluation of an Asphalt Binder Modified by Nano-TiO2.
Not available
S-EPMC9145936 | biostudies-literature
TranscriptomicsTranscription profiling by array of Huh7.5 cells infected with Hepatitis C Virus Jc1
Huh7/5-2 cells (Binder et al., Hepatology 2007) were mock infected (DMEM) (time points 4 and 48 h) or infected with the chimeric HCV virus Jc1 (Pietschmann et al., PNAS 2006) (all time points). Multiplicity of infection was 15 (TCID50). Cells were lysed after 4, 12, 24, 48 and 72 hours post infecti...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-MTAB-1148 | biostudies-arrayexpress
GenomicsEffect of DNA G-quadruplex binder on tumor cell line SAS
Effect of DNA G-quadruplex binder on tumor cell line SAS
PRJNA925560 | ENA
ProteomicsProtein binder based IP-MS of SLC12A6 (KCC3) in Hek293WT OE cell lines
Specific protein binders with high affinity, such as antibodies or nanobodies, are scarce for most solute carrier (SLCs) transporters. Moreover, general approaches that can systematically generate binders for multi-transmembrane proteins, such as SLCs, channels or GPCRs, are still missing. Purifying...
ORGANISM(S): Homo sapiens (Human) 
2024-06-17 | PXD046995 | Pride
Human Ip-ms Slc12a6 (kcc3) Protein binders 
ClinicalThe GI Binder: A Psychoeducational Intervention for Gastrointestinal Cancer Patients
This research study is evaluating the use of a binder of educational materials with nurse teaching to prepare patients for chemotherapy
2276899 | ecrin-mdr-crc
UnknownReduced Graphene Oxide as a Monolithic Multifunctional Conductive Binder for Activated Carbon Supercapacitors.
Not available
S-EPMC6120737 | biostudies-literature
GenomicsOptimal pairing of binder and costimulatory domains improves dual CAR T cell efficacy
Optimal pairing of binder and costimulatory domains improves dual CAR T cell efficacy
PRJNA1257323 | ENA
UnknownHyperkalemia treatment modalities: A descriptive observational study focused on medication and healthcare resource utilization.
Not available
S-EPMC6946143 | biostudies-literature
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