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Genome-wide location analysis of transcription factor of c-Myc and Max was conducted using RenLab Hu6K array in Daudi cells. In comparison, the GWLA was also done for general transcription factor RNA polymerase II and TAF1, and sequence specific transcription factor E2F1 in the same cell line. Keyw...
ORGANISM(S): Homo sapiens 
HIC data for 1kg trios Hi-C data was generated for the thousand genomes project SV group by the laboratory of Bing Ren. under an embargo and cannot be used in independent publications until February 1, 2017. Please direct correspondence to the UCSD PIs Bing Ren (biren@ucsd.edu) and Jonathan Sebat (j...
Aging was long assumed to be a passive and stochastic process caused by random damage accumulation, however,such theories fail to explain the program-like features of the aging process. Measuring the aging process in C. elegans at individual level provides an opportunity to analyze both the programm...
ORGANISM(S): Caenorhabditis elegans 
2023-11-14 | PXD039330 | Pride
Chronic infections by hepatitis B virus (HBV) and hepatitis C virus (HCV) appear to be the most significant causes of hepatocellular carcinoma (HCC). Aberrant promoter methylation is known to be deeply involved in cancer, including HCC. In this study, we analyzed aberrant promoter methylation on gen...
ORGANISM(S): Homo sapiens 
Micro-C was carried out for control embryos and embryos produced from gd7 mutant mothers. The embryos from mutant mothers produce only a single type along the dorsal-ventral axis (dorsal ectoderm). We used these embryos to compare chromatin conformation across tissues.
ORGANISM(S): Drosophila melanogaster 
Unraveling the complexity of transcriptional programs coded by different cell types has been one of the central goals of cell biology. Using genome-wide location analysis, we examined how two different cell types generate different responses to the NF-kappaB signaling pathway. We showed that, after ...
ORGANISM(S): Homo sapiens 
4DNESSSDVO27 - Replicate experiments of in situ Hi-C on CyT49 with MboI
Millions of cis-regulatory sequences have recently been found in the human genome, but the function of most cis-elements are not yet clear, in part due to the difficulty in determining their regulatory targets, which are often located millions of base pairs away and separated by one or more unrelate...
ORGANISM(S): Homo sapiens 
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