Biochemical pathway evolution

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Department of Glycobiology, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia (1)
Professor. Tier 1 Canada Research Chair in Marine Microbial Genomics and Biogeochemistry. Department of Biology, Dalhousie University (1)
Gregor Mendel Institute of Molecular Plant Biology GmbH Dr. Bohr-Gasse 3, 1030 Vienna, Austria Phone: +43 1 79044 9850 http://www.gmi.oeaw.ac.at (1)
Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS) (1)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (1)

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Adaptive evolution in yeast

A Saccharomyces cerevisiae population was cultured for many generations under conditions to which it is not optimally adapted. These experiments were designed to investigate adaptive evolution under natural selection. This study is described in more detail in Ferea TL, et al. 1999. Proc Natl Acad Sc...

ORGANISM(S): Saccharomyces cerevisiae

2002-02-11 | E-GEOD-29 | biostudies-arrayexpress

RNA-seq of wine yeast strains, parental and adaptively evolved for selective increase in aroma compounds originating in branched-chain or aromatic amino acid pathway

Adaptive laboratory evolution is highly effective for improving desired traits through natural selection. However, its applicability is inherently constrained to growth-correlated traits precluding traits of interest that incur a fitness cost, such as metabolite secretion. Here, we introduce the con...

ORGANISM(S): Saccharomyces cerevisiae

2021-12-30 | E-MTAB-10019 | biostudies-arrayexpress

The effects of repeated whole genome duplication events on the evolution of cytokinin signaling pathway.

Not available

S-EPMC5975490 | biostudies-literature

Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production

PRJEB32954 | ENA

Analysis of miRNA, piRNA and siRNA in Caenorhabditis species

The nematode Caenorhabditis elegans contains each of the broad classes of eukaryotic small RNAs, including microRNAs (miRNAs), endogenous small-interfering RNAs (endo-siRNAs) and piwi-interacting RNAs (piRNAs). To better understand the evolution of these regulatory RNAs, we deep sequenced small RNAs...

ORGANISM(S): Caenorhabditis elegans

2012-10-11 | E-GEOD-41461 | biostudies-arrayexpress

Inferring Biochemical Reactions and Metabolite Structures to Understand Metabolic Pathway Drift.

Not available

S-EPMC6997860 | biostudies-literature

Biochemical Evolution of a Potent Target of Mosquito Larvicide, 3-Hydroxykynurenine Transaminase.

Not available

S-EPMC9369995 | biostudies-literature

Model-guided development of evolutionarily stable yeast chassis for dicarboxylic acids production

Chassis strain suitable for producing multiple compounds is a central concept in synthetic biology. Design of a chassis using computational, first-principle, models is particularly attractive due to the predictability and control it offers, including against phenotype reversal due to adaptive mut...

2021-07-19 | MTBLS2007 | MetaboLights

Evolution of flux control in the glucosinolate pathway in Arabidopsis thaliana.

Not available

S-EPMC3525143 | biostudies-literature

Rapid evolution and conserved function of the piRNA pathway.

Not available

S-EPMC6367137 | biostudies-literature

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