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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
MetabolomicsAtlas of one-carbon metabolism in conventional and germ-free mice reveals folate as a key determinant of biochemical pathways

Folates participate in the one-carbon metabolism (OCM) cycle, supporting many biochemical pathways. Existing methods to profile folate are limited in the diversity of vitamers they measure and the samples they profile. We present a metabolomics workflow for stable extraction, separation, and meas...

2026-02-10 | MTBLS13484 | MetaboLights
UnknownPurification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris.
Not available
S-EPMC3989067 | biostudies-literature
UnknownA scalable method for biochemical purification of Salmonella flagellin.
Not available
S-EPMC4175188 | biostudies-literature
UnknownA bacterial chloroform reductive dehalogenase: purification and biochemical characterization.
Not available
S-EPMC5658581 | biostudies-literature
ProteomicsBiochemical and Structural Basif for Differential Inhibitor Sensitivity of EGFR with Distinct Exon 19 Mutaions
Tyrosine kinase inhibitors (TKIs) are used to treat non-small cell lung cancers (NSCLC) driven by epidermal growth factor receptor (EGFR) mutations in the tyrosine kinase domain (TKD). We studied structural basis of differential TKI sensitivity among EGFR exon 19 mutants by HDX-MS.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037374 | Pride
Exon 19 Hdx-ms Egfr 
UnknownExpression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli.
Not available
S-EPMC11143474 | biostudies-literature
UnknownA semi-automated method for purification of milligram quantities of proteins on the QIAcube.
Not available
S-EPMC4287359 | biostudies-literature
UnknownLarge-scale purification of functional human P-glycoprotein (ABCB1).
Not available
S-EPMC6600825 | biostudies-literature
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