Bioorthogonal chemistry

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Bioorthogonal Photocatalytic Proximity Labeling in Primary Living Samples

In situ profiling of subcellular proteomic networks in primary and living systems, such as primary cells from native tissues or clinic samples, is crucial for the understanding of life processes and diseases, yet challenging for the current proximity labeling methods (e.g., BioID, APEX) due to their...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2024-05-24 | PXD045791 | Pride

Light-activated tetrazines enable precision live-cell bioorthogonal chemistry.

Not available

S-EPMC10198265 | biostudies-literature

Impact of azide metabolic glycoengineering and bioorthogonal click chemistry cell-cell tethering in adipose tissue-derived mesenchymal stromal cells

We report RNA sequencing data from adipose tissue-derived mesenchymal stromal cells (hASCs) functionalized via metabolic glycoengineering with pendant azide sialosides. Beyond the impact of this cell surface engineering on transcriptome, we explore the expression profiles of azide-hASCs covalently t...

ORGANISM(S): Homo sapiens

2024-04-15 | GSE231507 | GEO

Directed Evolution of Enzymes for Bioorthogonal Chemistry Using Acid Chloride Proximity Labeling

PRJNA1404102 | ENA

Bioorthogonal chemistry-based RNA labeling technologies: evolution and current state.

Not available

S-EPMC7611129 | biostudies-literature

Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development.

Not available

S-EPMC4335810 | biostudies-literature

Reactive polymer enables efficient in vivo bioorthogonal chemistry.

Not available