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MetabolomicsCharacterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform
The exposome, defined as the cumulative measure of external exposures and associated biological responses throughout the lifespan, has emerged in recent years as a cornerstone in biomedical sciences. Metabolomics stands out here as one of the most powerful tools for investigating the interplay betwe...
2022-02-17 | MTBLS1906 | MetaboLights
MetabolomicsCharacterization of Yak Common Biofluids Metabolome by Means of Proton Nuclear Magnetic Resonance Spectroscopy
The aim of this study was to evaluate the metabolic profiles of yak (Bos grunniens) serum, feces, and urine by using proton nuclear magnetic resonance (1H-NMR), to serve as a reference guide for the healthy yak milieu. A total of 108 metabolites, giving information about diet, protein digestion, and...
2019-03-27 | MTBLS841 | MetaboLights
MetabolomicsLipid Data Analyzer: Novel lipid species and identification of regio-isomeric lipid species (HCD characterization and regioisomer detection)
Lipid Data Analyzer (LDA; http://genome.tugraz.at/lda2) provides automated and reliable annotation of lipid species and their molecular structures in high-throughput data from chromatography-coupled tandem mass spectrometry using embedded rule sets. Using various low- and high-resolution mass spectr...
2017-11-07 | MTBLS462 | MetaboLights
MetabolomicsCharacterization of small intracellular vesicles uncovers their potential as drug carriers and therapeutic agents

Small extracellular vesicles (sEVs) have been extensively investigated as a source of clinically relevant cargo. Alongside the secretion of EVs, such as exosomes, cells house a multitude of internal vesicles involved in various physiologic processes and metabolic activities. Herein, we developed ...

2025-09-02 | MTBLS12923 | MetaboLights
MetabolomicsIntegrated pharmacological and metabolomic characterization of a polysaccharide-enriched fraction from Qingfei-Paidu Decoction for protection against acute lung injury in mice
The formula of Qingfei-Paidu Decoction was separated into a polysaccharide-enriched fraction (PSC) and an ethanol-soluble small-molecule fraction (EtOH), whose biological activities were systematically compared under equivalent crude drug conditions using an LPS-induced ALI mouse model and macrophag...
2026-10-05 | MTBLS15898 | MetaboLights
UnknownThe utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies.
Not available
S-EPMC3164548 | biostudies-literature
UnknownAccelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning.
Not available
S-EPMC11790971 | biostudies-literature
UnknownCocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin.
Not available
S-EPMC10536922 | biostudies-literature
UnknownComprehensive Assessment of Protein and Excipient Stability in Biopharmaceutical Formulations Using 1H NMR Spectroscopy.
Not available
S-EPMC7906489 | biostudies-literature
UnknownMicrowell Plate-Based Dynamic Light Scattering as a High-Throughput Characterization Tool in Biopharmaceutical Development.
Not available
S-EPMC7911513 | biostudies-literature
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