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GenomicsSelective chemical labeling reveals intragenic enrichment of 5-hydroxymethylcytosine in mouse cerebellum
5-Methylcytosine (5-mC) is an important DNA modification found in eukaryotes that impacts gene regulation and disease pathogenesis. Recently, 5-hydroxymethylcytosine (5-hmC), another form of DNA modification, has been identified in substantial amounts in certain mammalian cell types; however, its ro...
ORGANISM(S): Mus musculus 
2010-12-12 | E-GEOD-25398 | biostudies-arrayexpress
ProteomicsSupplementary Dataset 10 - Alkyne-2PCA clicked to biotin-azide enrichment with E coli proteome-derived peptide libraries
Alkyne-2PCA clicked to biotin-azide enrichment with E coli proteome-derived peptide libraries
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-02-11 | MSV000091255 | MassIVE
ProteomicsSupplementary Dataset 14 - Alkyne-2PCA clicked to biotin-Diazo-azide enrichment with E coli proteome derived peptide libraries
Alkyne-2PCA clicked to biotin-Diazo-azide enrichment with E coli proteome derived peptide libraries
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-02-11 | MSV000091260 | MassIVE
ProteomicsSupplementary Dataset 11 - Alkyne-2PCA clicked to biotin-disulfide-azide enrichment with E coli proteome derived peptide libraries
Alkyne-2PCA clicked to biotin-disulfide-azide enrichment with E coli proteome derived peptide libraries
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-02-11 | MSV000091257 | MassIVE
ProteomicsSupplementary Dataset 12 - Alkyne-2PCA clicked to biotin-DADPS-azide enrichment with E coli proteome derived peptide libraries
Alkyne-2PCA clicked to biotin-DADPS-azide enrichment with E coli proteome derived peptide libraries
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-02-11 | MSV000091258 | MassIVE
ProteomicsSupplementary Dataset 13 - Alkyne-2PCA clicked to biotin-Dde-azide enrichment with E coli proteome derived peptide libraries
Alkyne-2PCA clicked to biotin-Dde-azide enrichment with E coli proteome derived peptide libraries
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-02-11 | MSV000091259 | MassIVE
UnknownBiotin-Conjugated Cellulose Nanofibers Prepared via Copper-Catalyzed Alkyne-Azide Cycloaddition (CuAAC) "Click" Chemistry.
Not available
S-EPMC7353318 | biostudies-literature
ProteomicsSupplementary Dataset 7 - Human proteome-derived peptide library generated with trypsin; treated with 10 mM alkyne-2PCA for 20 h at 37C; clicked with biotin azide
Human proteome-derived peptide library generated with trypsin; treated with 10 mM alkyne-2PCA for 20 h at 37C; clicked with biotin azide
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-11 | MSV000091252 | MassIVE
ProteomicsPATCH labeling in the BSA through red light
For the liquid chromatography-mass spectrometry (LC-MS) analysis, the 500 μM AP was used to label BSA in the reaction, followed by clicking chemical conjugation with 0.1 mM azide-PEG3-biotin under 0.5 mM CuCl(2), 2 Mm Tris (3-hydroxypropyltriazolylmethyl) amine (THPTA, Sigma-Aldrich) and 5 mM ascorb...
ORGANISM(S): Bos taurus (Bovine) 
2025-07-30 | PXD057016 | Pride
Pcn bsa 
ProteomicsFast and highly efficient affinity enrichment of Azide-A-DSBSO cross-linked peptides.
Cross-linking mass spectrometry is an increasingly used, powerful technique to study protein-protein interactions or to provide structural information. Due to sub-stochiometric reaction efficiencies, cross-linked peptides are usually low abundant. This results in challenging data evaluation and the ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2020-05-11 | PXD016963 | Pride
Click reaction Affinity enrichment Cross-linking Mass spectrometry Dbco Dsbso 
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