Sort   by:  
 Page size 
MetabolomicsGut Microbiome and Metabolome Alterations in Mice with Arsenic Exposure and Antibiotic Treatment: Potential Role of Arsenic Biotransformation Genes

Arsenic is the most prevalent toxic metalloid in environment. Evidence of mouse models (germ-free or antibiotic treatment) indicates the gut microbiota’s involvement in the metabolism of ingested arsenic. Linking genes to gut microbial arsenic metabolism with altered toxicity and lifetime in the ...

2025-05-12 | MTBLS11508 | MetaboLights
MetabolomicsMechanistic Insights into Lactic Acid Bacteria-Driven Biotransformation of Undaria pinnatifida: Ecological Dominance, Metabolic Reprogramming, and Quality Formation
Undaria pinnatifida, a representative brown macroalga, is limited in high-value food applications due to its dense cell wall structure, pronounced marine odor, and inefficient conventional processing. In this study, a controlled fermentation strategy was established using different lactic acid bacte...
2026-05-20 | MTBLS14540 | MetaboLights
MetabolomicsRapid biotransformation of STW 5 constituents by human gut microbiome from IBS- and non-IBS donors

STW 5, a blend of 9 medicinal plant extracts, exhibits promising efficacy in treating functional gastrointestinal disorders, notably irritable bowel syndrome (IBS). Nonetheless, its effects on the gastrointestinal microbiome and the role of microbiota on the conversion of its constituents are sti...

2024-05-07 | MTBLS2398 | MetaboLights
MetabolomicsTime-Resolved Microbiome–Metabolome Remodeling Reveals Biotransformation Patterns in Liquid-Fermented Dendrobium officinale Flowers
This study investigated temporal metabolomic changes during a 60-day mixed-culture liquid fermentation of Dendrobium officinale flowers. Fermentation supernatants were collected at days 10, 20, 30, 40, 50, and 60, with six biological replicates at each time point. Untargeted LC-MS/MS analysis was pe...
2026-07-22 | MTBLS15132 | MetaboLights
MetabolomicsBiotransformation causes the sex-specific regulation of polychlorinated biphenyls during metamorphosis of silkworm (Bombyx mori) and their effect on the silkworm development

The decline in insect populations is indisputable. Currently, the effects of persistent organic pollutants on insect populations have not been sufficiently investigated. Maternal transfer of pollutants is considered to be an inherently correct reason for sex differences in pollutant le...

2025-09-09 | MTBLS12906 | MetaboLights
MetabolomicsComprehensive biotransformation analysis of phenylalanine-tyrosine metabolism reveals alternative routes of metabolite clearance in nitisinone-treated alkaptonuria (Urine metabolomic analysis)
Not available
ORGANISM(S): Homo sapiens 
ST002297 | MetabolomicsWorkbench
MetabolomicsComprehensive biotransformation analysis of phenylalanine-tyrosine metabolism reveals alternative routes of metabolite clearance in nitisinone-treated alkaptonuria (Serum metabolomic analysis)
Not available
ORGANISM(S): Homo sapiens 
ST002296 | MetabolomicsWorkbench
GenomicsTOrCs biotransformation
TOrCs biotransformation, microbial composition and functional potential in biofiltration systems
PRJEB43767 | ENA
MetabolomicsElucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells

Environmental exposure to xenoestrogens, i.e., chemicals that imitate the hormone 17β-estradiol, has the potential to influence hormone homeostasis and action. Detailed knowledge of xenobiotic biotransformation processes in cell models is key when transferring knowledge learned from in vitro<...

2023-10-26 | MTBLS2716 | MetaboLights
ProteomicsProteomic analysis of Ganoderma sessile biotransformation of 15,16-dihydrotanshinone Ⅰ to obtain ganoderic acid
Biotransformation of 15,16-dihydrotanshinone Ⅰto shaker-cultured Ganoderma sessile mycelium to produce ganoderic acid, proteomic analysis of biotransformed mycelium and normal G. lsessile mycelium
ORGANISM(S): Ganoderma Sessile 
2023-03-07 | PXD040674 |
Sort   by:  
 Page size