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Single-cell RNA sequencing (scRNA-seq) was performed on longitudinal CD4⁺ T-cell samples from 11 children who later developed type 1 diabetes and 11 matched controls. Samples were collected prior to or at the time of type 1 diabetes–specific autoantibody appearance (seroconversion), between ages 3 a...
ORGANISM(S): Homo sapiens 
We induced EAE in mice carrying a gene-trap disruption of Cip2a (hereafter referred to as knockout [KO] mice) and wild-type (WT) control C57BL/6J male and female mice, aged 8-12 weeks. We performed scRNA-seq analysis of lymph node cells from five WT and five KO mice at the peak of EAE. The goal was ...
ORGANISM(S): Mus musculus 
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