Sort   by:  
 Page size 
ProteomicsAutoinhibition of Trio guanine nucleotide exchange factor activity for Rac1 by its spectrin repeats is disrupted by neurodevelopmental disorder-related genetic variants
Crosslinking MS of SR6-GEF1 construct of Human Trio. BS3 crosslinking of wild-type and three point mutants implicated in neurodevelopmental disorders (E883D, R1078Q, D1368V). Data acquired using FAIMS ion mobility source with each sample acquired at 4 different CVs (-40, -50, -60, -70V).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-08 | MSV000089621 | MassIVE
UnknownMethylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids.
Not available
S-EPMC9338451 | biostudies-literature
UnknownRadical chain repair: The hydroalkylation of polysubstituted unactivated alkenes.
Not available
S-EPMC6054511 | biostudies-literature
UnknownDivergent Bacterial Communities in Water and Sediment of Chlorinated Drinking Water Storage Tanks.
Not available
S-EPMC12797242 | biostudies-literature
UnknownEvaluation of nursing process competencies, nursing quality, and patient safety using virtual simulation with debriefing: A quasi-experimental study.
Not available
S-EPMC10520815 | biostudies-literature
ProteomicsAutoinhibition of Trio guanine nucleotide exchange factor activity for Rac1 by its spectrin repeats is disrupted by neurodevelopmental disorder-related genetic variants.
Function-damaging variants in the TRIO gene are enriched in individuals with neurodevelopmental disorders (NDDs). TRIO encodes a cytoskeletal regulatory protein with three catalytic domains – two guanine exchange factor (GEF) domains, GEF1 and GEF2, and a kinase domain, as well as several accessory ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-13 | PXD034393 | Pride
Limited proteolysis Neurodevelopment disorders Trio gene Crosslinking 
UnknownAre insect bites responsible for the rise in summer flucloxacillin prescribing in United Kingdom general practices?
Not available
S-EPMC10745258 | biostudies-literature
UnknownStrict sun protection results in minimal skin changes in a patient with xeroderma pigmentosum and a novel c.2009delG mutation in XPD (ERCC2).
Not available
S-EPMC2605190 | biostudies-literature
UnknownIntestinal epithelial PTPN23 is essential for gut barrier integrity and prevention of fatal bacterial translocation.
Not available
S-EPMC11815487 | biostudies-literature
ProteomicsCommensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
We identified certain members of the gut microbiota associated with a lower tumor burden in mouse models of colorectal cancer (CRC). Orally applied, a mix of four Clostridiales strains (CC4) prevented and even successfully treated CRC as a stand-alone therapy.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-06-15 | MSV000087624 | MassIVE
Sort   by:  
 Page size