Sort   by:  
 Page size 
ProteomicsYPIC challenge 2018: A case study in characterizing an unknown protein sample
For the YPIC challenge 2018 contestants were invited to try to decipher two unknown English questions encoded by a synthetic protein expressed in E. coli. We present how we analyzed this unknown sample using a tryptic digest with dynamic exclusion disabled to increase the signal-to-noise ratio of t...
ORGANISM(S): Escherichia coli 
2019-06-11 | PXD014003 | Pride
Spectral clustering Spectral networking Ypic De novo Synthetic protein 
ProteomicsFast open modification spectral library searching through approximate nearest neighbor indexing
Open modification searching (OMS) is a powerful search strategy that identifies peptides carrying any type of modification by allowing a modified spectrum to match against its unmodified variant by using a very wide precursor mass window. A drawback of this strategy, however, is that it leads to a l...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2021-05-25 | PXD009861 | Pride
Ptm Open modification searching Spectral library 
ProteomicsExtremely fast and accurate open modification spectral library searching of high-resolution mass spectra using feature hashing and graphics processing units
Open modification searching (OMS) is a powerful search strategy to identify peptides with any type of modification. OMS works by using a very wide precursor mass window to allow modified spectra to match against their unmodified variants, after which the modification types can be inferred from the c...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2019-12-06 | PXD013641 | Pride
Proteomics Graphics processing unit Post-translational modification Mass spectrometry Feature hashing Approximate nearest neighbor indexing Spectral library Open modification searching 
MetabolomicsFour layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequenc...

2022-09-19 | MTBLS1612 | MetaboLights
MetabolomicsGNPS - NISTfecalRM_Astral_HypersilGoldC18_positive
NIST fecal reference material extracted with 50% MeOH and prepared in different dilutions and reconstitution solvents. The analysis was conducted using a Hypersil Gold (C18) in positive ionization mode on a Astral via different MS-modes (positive ionization mode).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-28 | MSV000093526 | GNPS
Sort   by:  
 Page size