Sort   by:  
 Page size 
ProteomicsCETSA proteomics to investigate drug binding in BJ Ras Sv40 cells treated with MTH1 inhibitors.
Previously, we showed cancer cells rely on the MTH1 protein to prevent incorporation of otherwise deadly oxidative nucleotides into DNA and we developed MTH1 inhibitors which selectively kill cancer cells. Recently, several new and potent inhibitors of MTH1 were demonstrated to be non-toxic to cance...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD004541 | Pride
Proteomics Lc-ms Bj ras sv40 cells Cetsa Human 
TranscriptomicsInvestigation of extra-telomeric effects of hTERT in neoplastic transformation of IMR90 cells
The complexity and heterogeneity of cancer cells are under-represented by the current experimental models which revolve around primary tumor cells, cancer cell lines, and rodent models. We used the transformed cell model in our studies. IMR90 and BJ fibroblast cells were transformed by three oncogen...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-24097 | biostudies-arrayexpress
UnknownMalignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE.
Not available
S-EPMC2955615 | biostudies-literature
TranscriptomicsInvestigation of extra-telomeric effects of hTERT in neoplastic transformation of IMR90 cells
The complexity and heterogeneity of cancer cells are under-represented by the current experimental models which revolve around primary tumor cells, cancer cell lines, and rodent models. We used the transformed cell model in our studies. IMR90 and BJ fibroblast cells were transformed by three oncogen...
ORGANISM(S): Homo sapiens 
2010-12-31 | GSE24097 | GEO
GenomicsHomo sapiens
Investigation of extra-telomeric effects of hTERT in neoplastic transformation of IMR90 cells
PRJNA130297 | ENA
TranscriptomicsA Transcriptional Signature and Common Gene Networks Link Cancer with Metabolic Syndrome and Auto-immune Diseases
Epidemiological studies have revealed concurrence of specific cancers with other disease states such as metabolic syndrome, inflammatory disease and autoimmune disease. Patients with these chronic conditions have a higher incidence of various cancers, more aggressive tumors, and a higher mortality r...
ORGANISM(S): Homo sapiens 
2010-04-19 | E-GEOD-17941 | biostudies-arrayexpress
Sort   by:  
 Page size