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ProteomicsTendon tissue degradome in response to the patho-physiological niche
Aberrant matrix turnover with elevated matrix proteolysis is a hallmark of tendon pathology. While tendon disease mechanisms remain obscure, mechanical cues are central regulators. Unloading of tendon explants in standard culture conditions provokes rapid cell-mediated tissue breakdown. Here we show...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-28 | PXD013635 | Pride
Mouse Tendon Thermo q exactive Tails 
TranscriptomicsRNA-seq of human mesenchymal stromal cells cultured in PEG hydrogels with and without FGF-2
FGF-2 is commonly used in culture media when growing mechenchymal stromal cells. Here, we cultured human MSCs from 3 donors with and without 50 ng/ml FGF-2 (Prepotech, human recombinant) in 3D PEG hydrogels, and analysed transcriptome changes by RNA sequencing.
ORGANISM(S): Homo sapiens 
2020-06-02 | E-MTAB-8510 | biostudies-arrayexpress
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