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MetabolomicsEffect of L-carnitine administration on lipid and metabolite content in sheep infraspinatus muscle after tendon release
Metabolites and lipid species were measured using ultrahigh performance lipid chromatography – tandem mass spectrometry in biopsies of infraspinatus muscle after 2 weeks of tendon release in the operated and contralateral muscle. A group of animals received oral treatment with L-carnitine.
2020-07-20 | MTBLS1490 | MetaboLights
MetabolomicsPostoperative Exercise Modulating Gut Microbiota and Associated Metabolites to Facilitate Bone-Tendon Healing in Rotator Cuff Tears

Background: Rotator cuff tear (RCT) is a prevalent shoulder injury, and postoperative exercise is considered to facilitate RCT healing. However, the effect of postoperative exercise on RCT healing through gut microbiota and metabolites remains unclear.

Method: The control (con) group (n=10...

2026-03-03 | MTBLS13894 | MetaboLights
TranscriptomicsRNA-seq of achilles tendon from young and old donors to study age-related changes in tendon
Tendon from young and old donors was used for RNA-Seq analysis. The aim of the study was to identify differentially expressed tendon transcripts in ageing in order to to characterize molecular mechanisms associated with age-related changes in tendon.
ORGANISM(S): Homo sapiens 
2015-04-01 | E-MTAB-2449 | biostudies-arrayexpress
MetabolomicsA Randomized Controlled Trial of Shengji Ointment Combined with Bromelain in Promoting Healing of Tendon-Exposed Diabetic Foot Wounds: Metabolomics Profiling Analysis

Background: Diabetic foot tendon exposures are prone to infection, necrosis, and prolonged treatment cycles, not only hindering wound healing but potentially leading to amputation and life-threatening complications. Shengji ointment combined with bromelain has demonstrated preliminary efficacy i...

2025-07-14 | MTBLS12713 | MetaboLights
ProteomicsGrafting induced pluripotent stem cells-derived tenocytes contribute to recovery of motor function after Achilles tendon rupture in rat
Self-renewal of tendons is rare since the vascular formation inside is extremely poor, thus reconstructive surgery using autologous tendons has been often taken place in the case of severe injury. However, the rate of re-injury after surgery is relatively high, and collection of autologous tendons l...
ORGANISM(S): Homo Sapiens (human) 
2021-07-01 | PXD020887 | JPOST Repository
TranscriptomicsMechanical shear effects on flexor tendon cells
Adhesion formation after flexor tendon repair remains a clinical problem. Early postoperative motion after tendon repair has been demonstrated to reduce adhesion formation while increasing tendon strength. It is hypothesized that during mobilization, tendon cells experience mechanical shear forces t...
ORGANISM(S): Mus musculus 
2006-01-27 | E-GEOD-4096 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Tendon fascicles were analysed directly after isolation from the tail of freshly euthanized mice and after of after ex vivo culture for 6 days. Fascicles were cultured in either serum containing medium (10%) or in serum-free medium at 21% oxygen and 37 degrees celsius.
ORGANISM(S): Mus musculus 
2020-09-15 | E-MTAB-9540 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mechanical shear effects on flexor tendon cells
Adhesion formation after flexor tendon repair remains a clinical problem. Early postoperative motion after tendon repair has been demonstrated to reduce adhesion formation while increasing tendon strength. It is hypothesized that during mobilization, tendon cells experience mechanical shear forces t...
ORGANISM(S): Mus musculus 
2005-11-09 | E-SMDB-3543 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of mechanically intact and degraded murine tail tendon fascicles after exposure to differential temperature and oxygen tension
Tendon fascicles were extracted from tails of freshly euthanized mice and cultured for 6 days ex vivo in serum containing medium (10%) at either 3% oxygen and 29 degrees celsius or 21% oxygen and 37 degrees celsius.
ORGANISM(S): Mus musculus 
2020-01-31 | E-MTAB-7832 | biostudies-arrayexpress
ProteomicsProteomic comparison study between female and male tendon
Tendons play fundamental role in the musculoskeletal system and locomotion by transferring forces generated by muscles to the skeleton. Chronic tendon injuries and diseases are among the leading causes of musculoskeletal disability. For many types of tendinopathies, women have worse clinical outcome...
ORGANISM(S): Mus musculus (Mouse) 
2017-01-16 | PXD004612 | Pride
Tendon Female Male Lc-ms/ms 
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