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TranscriptomicsTranscription profiling of skeletal and cardiac muscles in dysferlin-deficient SJL/J mice and wild type mice to understand the protective mechanisms against dysferlin deficiency in cardiac muscles.
Dysferlin is expressed in skeletal and cardiac muscle. However, dysferlin deficiency, namely limb girdle muscular dystrophy 2B (LGMD2B) and Myoshi myopathy, results in skeletal muscle weakness and spares the heart. This dichotomy could be caused by differential regulation of protective mechanisms. T...
ORGANISM(S): Mus musculus 
2007-09-04 | E-GEOD-2507 | biostudies-arrayexpress
UnknownJim Crow and premature mortality among the US Black and White population, 1960-2009: an age-period-cohort analysis.
Not available
S-EPMC4710482 | biostudies-literature
UnknownEducation in the Jim Crow South and Black-White inequities in allostatic load among older adults.
Not available
S-EPMC9482141 | biostudies-literature
UnknownAdverse events in patients treated with neoadjuvant chemo/immunotherapy for triple negative breast cancer: results from seven academic medical centers.
Not available
S-EPMC12259778 | biostudies-literature
TranscriptomicsLymph node CD4+ T cell and thioglycollate-elicited peritoneal macrophage expression data from naM-CM-/ve young and old SJL/J and SJL-ChrY^B10.S male mice
Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases. Here, using chromosome Y (ChrY) consomic mouse strains on the C57BL/6J background, we show that susceptibility to two diverse animal models of ...
ORGANISM(S): Mus musculus 
2013-05-28 | E-GEOD-47437 | biostudies-arrayexpress
TranscriptomicsGene expression profile of influenza virus antigen-activated or in vitro stimulated murine CD8+ T cells on day 7
The precise timing and pathway of memory CD8+ T cells differentiation from naïve T cells have remained undetermined. We found the smaller cell-size and slower cell cycling cells were segregated from the proliferative larger cell-size activated T cell pool at the peak of infection. Gene signature of ...
ORGANISM(S): Mus musculus 
2015-02-25 | E-GEOD-48219 | biostudies-arrayexpress
UnknownEpigenetic aging in older breast cancer survivors and noncancer controls: preliminary findings from the Thinking and Living with Cancer Study.
Not available
S-EPMC10659047 | biostudies-literature
UnknownRacial disparities in children tested for SARS-CoV-2 at pediatric emergency departments: A prospective cohort study.
Not available
S-EPMC12718024 | biostudies-literature
UnknownHypoxia drives transient site-specific copy gain and drug-resistant gene expression.
Not available
S-EPMC4441050 | biostudies-literature
TranscriptomicsTranscriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue
Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at the spatial resolution of a single cell. Current capture methods lack sufficient spatial resolution to isolate mRNA from individual in vivo re...
ORGANISM(S): Mus musculus 
2014-01-12 | E-GEOD-52525 | biostudies-arrayexpress
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