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UnknownEvidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.
Not available
S-EPMC104391 | biostudies-literature
TranscriptomicsGlobal Analysis of Post-transcriptional Gene Expression in Arsenite-treated Human BJ Fibroblasts
Arsenic is a potent environmental toxin and a cause of numerous health problems. Most studies have assumed that arsenic-induced changes in mRNA levels result from effects on gene transcription. The influence of arsenic on post-transcriptional regulation, another important locus of gene expression ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-57051 | biostudies-arrayexpress
TranscriptomicsPost-transcriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in S. pombe
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind directly to AU-rich elements in mRNAs and promote transcript deadenylation and decay. The yeast Schizosaccharomyces pombe expresses a single TTP family member, Zfs1p, that has been linked to the mating response...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-06 | E-GEOD-35009 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiling of spontaneous mesotheliomas in F344N rats
Aged male Fischer 344/N rats are prone to developing spontaneous peritoneal mesotheliomas, which arise predominantly from the tunica vaginalis of the testes. A definitive cause for the predominance of this neoplasm in F344/N rats is unknown. Investigation of the molecular alterations that occur in s...
ORGANISM(S): Rattus norvegicus 
2013-09-06 | E-GEOD-47581 | biostudies-arrayexpress
TranscriptomicsTristetraprolin (TTP) regulated splenic transcriptome in "Triple KO" mice
Tristetraprolin (TTP) binds to specific AU-rich elements in the 3'UTR of certain transcripts and regulates post-transcriptional gene expression by increasing the rate of mRNA turnover. In this study, we evaluated the effects of TTP deficiency on the overall gene expression of spleen tissue, in ord...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-60243 | biostudies-arrayexpress
UnknownRelation of Carotid Intima-Media Thickness to Cardiovascular Events in Black Americans (From the Jackson Heart Study).
Not available
S-EPMC5640488 | biostudies-literature
UnknownPterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial.
Not available
S-EPMC4099343 | biostudies-literature
UnknownResting Heart Rate and Long-term Outcomes Among the African American Population: Insights From the Jackson Heart Study.
Not available
S-EPMC5310994 | biostudies-literature
UnknownUnraveling the Easix Score: Its Association with Vasopressor Need in Critically Ill Septic Pediatric Hematology-Oncology Patients.
Not available
S-EPMC12524857 | biostudies-literature
UnknownZFP36L2 Role in Thyroid Functionality.
Not available
S-EPMC8431063 | biostudies-literature
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