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ProteomicsFibroblast growth factor 2 promotes bladder hypertrophy caused by partial bladder outlet obstruction
The current study aims to investigate molecular alterations and biomarkers associated with partial BOO (PBOO) in rats.TMT-Labeling Proteomic Analysis of PBOO Bladder Tissues at Week 5.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-10 | PXD024378 | Pride
Bladder outlet obstruction Rat Bladder hypertrophy 
TranscriptomicsTranscription profiling of human bladder tumours to construct a tumour stage classifier
Bladder tumours used to construct a tumour stage classifier
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-89 | biostudies-arrayexpress
TranscriptomicsProstates of rats with induced partial bladder outlet obstruction and the effect of Eviprostat on those changes
Prostatic inflammation plays a role in the progression of benign prostatic hyperplasia (BPH). Eviprostat is an antiinflammatory and antioxidant phytotherapeutic agent widely used to treat lower urinary tract symptoms in BPH. However, because Eviprostat is a mixture of compounds from multiple natural...
ORGANISM(S): Rattus norvegicus 
2010-04-09 | E-GEOD-16063 | biostudies-arrayexpress
GenomicsFibroblast growth factor 2 promotes bladder hypertrophy caused by partial bladder outlet obstruction
Fibroblast growth factor 2 promotes bladder hypertrophy caused by partial bladder outlet obstruction
PRJNA704641 | ENA
GenomicsGATA-6 and NFkB Repress Caveolins Transcription in Bladder Smooth Muscle Hypertrophy
GATA-6 and NFkB Repress Caveolins Transcription in Bladder Smooth Muscle Hypertrophy
PRJNA420061 | ENA
TranscriptomicsTranscription profiling of human bladder smooth muscle cells subjected to cyclic stretch-relaxation
The aim of the experiment was to determine the effect of cyclic stretch-relaxation ("stretch") on gene expression patterns in normal diploid human bladder smooth muscle cells. Cells plated on silicone elastomer bottomed 6-well culture dishes were grown to ~80% confluence, serum-depleted for 48h and ...
ORGANISM(S): Homo sapiens 
2007-08-04 | E-GEOD-1595 | biostudies-arrayexpress
TranscriptomicsPKCzeta-mediated Gaq stimulation of the ERK5 pathway is involved in cardiac hypertrophy
Background: Gq-coupled G protein-coupled receptors (GPCR) mediate the actions of a variety of messengers that are key regulators of cardiovascular function. Enhanced Gaq-mediated signaling plays an important role in cardiac hypertrophy and in the transition to heart failure. We have recently describ...
ORGANISM(S): Mus musculus 
2012-01-10 | E-GEOD-29145 | biostudies-arrayexpress
TranscriptomicsFibroblast growth factor 2 promotes bladder hypertrophy caused by partial bladder outlet obstruction
The current study aims to investigate molecular alterations and biomarkers associated with partial BOO (PBOO) in rats. RNA-seq analyses were conducted to identify molecular alterations. Rats with PBOO experienced hypertrophy of smooth muscle cells and hyperplasia of interstitial cells during the fir...
ORGANISM(S): Rattus norvegicus 
2021-04-20 | GSE167430 | GEO
TranscriptomicsGATA-6 and NFkB Repress Caveolins Transcription in Bladder Smooth Muscle Hypertrophy
Microarray analysis of bladder RNA revealed down-regulation of CAV1, CAV2 and CAV3 gene transcription in both mice with obstruction-induced BSM hypertrophy, and in men with benign prostatic hyperplasia Knockout of NF-κB subunits or shRNA-mediated knockdown of GATA-6 in BSM increased CAV1, CAV2 and C...
ORGANISM(S): Mus musculus 
2018-12-17 | GSE107427 | GEO
UnknownFibroblast Growth Factor 2 Promotes Bladder Hypertrophy Caused by Partial Bladder Outlet Obstruction.
Not available
S-EPMC8042216 | biostudies-literature
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