Blair Alexander A

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A comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans

DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass spectrometry-based adductomics (LC-MS/MS) to define the landscape of D...

ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat)

2023-09-12 | PXD045311 | Pride

Adductomics Strp mrm

Single-cell RNA and BCR sequencing of naive B cells cultured in IgG class-switching polarising conditions

Naive B cells (CD27-IgD+) were obtained from 3 healthy controls and cultured in vitro under anti-IgM, CD40L and IFN-gamma to polarise class-switching towards IgG isotypes. Single-cell RNA and BCR sequencing libraries were prepared at Day 0 (before addition of stimuli), Day 3 and Day 6 of the cell cu...

ORGANISM(S): Homo sapiens

2023-07-01 | E-MTAB-13050 | biostudies-arrayexpress

The influence of scale-dependent geodiversity on species distribution models in a biodiversity hotspot.

Not available

S-EPMC10859231 | biostudies-literature

Mass Spectrometry-Based Lipidomics of Brown Adipose Tissue and Plasma of New-Born Lambs Subjected to Short-Term Cold Exposure.

Not available

S-EPMC9597848 | biostudies-literature

Pesticide exposure and risk of aggressive prostate cancer among private pesticide applicators.

Not available

S-EPMC7059337 | biostudies-literature

A systematic review of in-patient psychiatric care for people with intellectual disabilities and/or autism: effectiveness, patient safety and experience.