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ProteomicsAllosteric priming of E. coli CheY by the flagellar motor protein FliM
We detail simulations and solution measurements to better understand the differences between the native and D13K-Y106W CheY crystal structures. We resolved the complex conformational landscapes by MD simulations with mutual information measures to determine the coupling between protein fragments. Pr...
ORGANISM(S): Escherichia coli BL21(DE3) 
2020-09-21 | PXD020434 | Pride
Xfms Chey Flim Atomistic simulation Flagellar 
TranscriptomicsGene Profiling in the Livers of Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctanoic Acid (PFOA)
Unlike the PPARalpha agonist W14,643, PFOA is capable of inducing effects independently of PPARa. Genes altered in the PPARalpha-null mouse following exposure to PFOA included those associated with fatty acid metabolism, inflammation, xenobiotic metabolism, and cell cycle progression. The specific s...
ORGANISM(S): Mus musculus 
2008-05-22 | E-GEOD-9796 | biostudies-arrayexpress
TranscriptomicsTest dataset for countASAP package: a lightweight easy to use Python package for processing ASAPseq data
A recently developed technique, transposase-accessible chromatin with sequencing (ATAC) with select antigen profiling by sequencing (ASAPseq), provides a combination of chromatin accessibility assessments with measurements of cell- surface marker expression levels. While software exists for the char...
ORGANISM(S): Mus musculus 
2025-10-24 | E-MTAB-15786 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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