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TranscriptomicsGenomic Characterization of Adaptive Mutations that Effect Minimal Fitness Trade-offs in Evolved Clones of Saccharomyces cerevisiae
In some of the earliest uses of genome-wide gene-expression microarrays and array-based Comparative Genomic Hybridization (aCGH), a set of diploid yeasts that had undergone experimental evolution under aerobic glucose limitation was used to explore how gene expression and genome structure had respon...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-02 | E-GEOD-25081 | biostudies-arrayexpress
TranscriptomicsExpression profile of third instar larval salivary gland tissue
We use mRNA-seq to transcriptionally profile larval salivary gland tissue from Drosophila third instar larvae. These data provide insights into tissue physiology and can be used to identify tissue specific transcripts. Salivary glands were dissected from 200 wandering third instar larvae and the ass...
ORGANISM(S): Drosophila melanogaster 
2011-10-18 | E-GEOD-33017 | biostudies-arrayexpress
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
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