Blood malignancies

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Unknown (4384)
Genomics (1063)
Transcriptomics (765)
Proteomics (206)
Metabolomics (113)
Clinical (25)
Methylation profiling (15)
Genomic (13)
Other (9)
Models (7)
Multiomics (3)

Organisms

Homo sapiens (1308)
Mus musculus (231)
Aerococcus urinae NBRC 15544 = CCUG 36881 (42)
Allexis (42)
Beta vulgaris subsp. vulgaris (42)
Canis lupus familiaris (42)
Carya cathayensis (42)
Clostridioides difficile 630 (42)
Cyanophora paradoxa (42)
Ensifer adhaerens (42)
Enterococcus faecalis (42)
Globicatella sanguinis (42)
Histomonas meleagridis (42)
Human immunodeficiency virus 1 (42)
Leishmania major strain Friedlin (42)
Listeria monocytogenes (42)
Lotus japonicus (42)
Marchantia polymorpha (42)
Canis lupus familiaris (8)
Danio rerio (4)
Rattus norvegicus (3)
Gallus gallus (2)
Drosophila melanogaster (2)
cellular organisms (2)
Panthera tigris altaica (1)
Vitis sp. cv. 'Norton' (1)
Aspergillus niger (1)
Sus scrofa (1)
Arabidopsis thaliana (1)
Mus (1)

Organisms

Homo sapiens (232)
Mus musculus (74)
Danio rerio (5)
Drosophila melanogaster (1)
Canis lupus familiaris (1)

Repository

biostudies-arrayexpress (683)
EGA (606)
ENA (359)
geo (204)
MetaboLights (112)
MassIVE (101)
pride (42)
jPOST (38)
iProX (21)
dbGaP (13)
BioModels (5)
EVA (3)
Cell Collective (2)
PeptideAtlas (2)
GNPS (1)

Tissue

Blood (14)
Blood cell (13)
Cell culture (6)
Blood serum (5)
Bone marrow (4)
B cell (3)
Epithelial cell (3)
T cell (3)
Others (2)
Brain (2)
Cell suspension culture (2)
Lung (2)
Myeloid cell (2)
Peripheral blood mononuclear cell (2)
Acute myeloid leukemia cell line (1)
Astrocyte (1)
B-cell lymphoma/leukemia 11B (1)
Blood plasma (1)
Blood platelet (1)
Breast cancer cell line (1)
Epithelial cell of lung (1)
Epithelial cell of skin gland (1)
Erythrocyte (1)
Generation of neurons (1)
HeLa cell (1)
Leukocyte (1)
Lymph node (1)
Lymphocytic leukemia cell (1)
Malignant cell (1)
Monocyte (1)

Disease

Burkitt Lymphoma (6)
Colorectal Neoplasms (5)
Normal (4)
Breast cancer (2)
Neuroblastoma (2)
Glioblastoma multiforme (1)
Cancer (1)
Endometrioid carcinoma (1)
Androgen-dependent prostate cancer (1)
Wilms' tumor (1)
Angioimmunoblastic T-cell lymphoma (1)
B-cell chronic lymphocytic leukemia (1)
Undifferentiated sarcoma (1)
Primary tumor (1)
Polycythemia vera (1)
Leukemia (1)
Giant Cell Glioblastoma (1)
Papillary thyroid carcinoma (1)
Obesity (1)
Chronic active EB virus infection (1)
Non-small cell lung carcinoma (1)
Extranodal NK/T cell lymphoma, nasal type (1)
Adenocarcinoma (1)
2) lymphoid malignancies (1)
Vaginal stenosis following radiotherapy (1)
Leukemia, Myeloid (1)
Peritoneal Diseases (1)
Colorectal cancer, Gastric cancer, Esophageal cancer, Biliary tract cancer, Pancreatic cancer, and Other Solid cancer (1)
Secondary malignant neoplasm of large intestine and rectum (1)
Neoplastic Syndromes, Hereditary (1)

Technology Type

Illumina HiSeq 2000 (9)
Illumina HiSeq 2500, ILLUMINA (7)
Illumina MiSeq (6)
ILLUMINA, Illumina HiSeq 2000 (5)
Illumina HiSeq 2500 (4)
ILLUMINA, HiSeq X Ten (2)
Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (2)
Illumina HiSeq 2500, Illumina HiSeq 2000 (2)
Illumina HiSeq 2000, ILLUMINA (2)
Illumina Genome Analyzer II (2)
NextSeq 500 (ILLUMINA), Illumina HiSeq 2500 (ILLUMINA) (1)
Illumina MiSeq, NextSeq 500, ILLUMINA (1)
ILLUMINA, Low Pass Whole Genome Sequencing (LP-WGS), Illumina NovaSeq 6000, Illumina Genome Analyzer II, SNP array (1)
Illumina CytoSNP, Illumina HumanOmni2.5, ILLUMINA, Illumina 450k, Illumina HiSeq 2000 (1)
Combined on identical nucleotide universal identifier, Illumina HumanWG-6 version 3 or Illumina HumanHT-12 expression bead chip (1)
Exiqon 7th generation miRCURY LNA microRNA microarray system (1)
Illumina HumanWG-6 (1)
Illumina HiSeq 2500 (ILLUMINA), Illumina HiSeq 4000 (ILLUMINA) (1)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 4000, ILLUMINA (1)
IlluminaHuman HT12, IlluminaHuman AWG-6 and HT12 (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Ion Torrent Proton, Illumina MiSeq, NextSeq 550 (1)
Illumina HiSeq 2500, SNP6.0, ILLUMINA (1)
Illumina HiSeq 2500, ILLUMINA, Illumina MiSeq (1)
AB 5500xl Genetic Analyzer (1)
Illumina HiSeq 2000, Illumina MiSeq (1)
Affymetrix 250K Nsp-GTYPE, Illumina HiSeq 2000 (1)
454 GS FLX Titanium, Illumina HiSeq 2000 (1)

Instrument Platform

Illumina NovaSeq 6000 (49)
Illumina NovaSeq X (12)
NextSeq 500 (12)
NextSeq 550 (10)
Illumina HiSeq 2500 (10)
Illumina HiSeq 2000 (8)
Illumina HiSeq 4000 (5)
NextSeq 2000 (3)
Tru-cut biopsy needle (Marquee®, 16 G × 10 cm) (2)
General usage Laborartory equipment (2)
Lab Centrifuge (2)
. (2)
None (2)
Not applicable (2)
NA (2)
DNBSEQ-G400 (2)
DNBSEQ-T7 (2)
HiSeq X Ten (2)
Maxwell® RSC 48 Instrument (Promega, AS8500) (1)
Transrectal ultrasound-guided systematic sampling of prostate tissue (TRUS biopsy) (1)
Affymetrix GCS 3000 (1)
GeneChip® Pico Kit (Affymetrix) (1)
Affymetrix Clariom™ S (400 Format) (1)
Cell Ranger (1)
Computational analysis using R (Seurat v5.0.0) (1)
Chromium Controller with Chromium Next GEM Single Cell 5’ and V(D)J (kits v1.1) (1)
TruSeq PCR-free Sample Preparation Kit (1)
BD Rhapsody Sequence Analysis Pipeline (1)
Aurora Cytek Cs 5L (1)
10X Genomics Single Cell, V3.1 (1)

Publication Date

2025 (137)
2013 (91)
2024 (88)
2026 (87)
2012 (71)
2014 (70)
2011 (69)
2010 (69)
2023 (66)
2016 (60)
2015 (57)
2022 (56)
2021 (48)
2020 (44)
2008 (41)
2009 (40)
2017 (28)
2019 (28)
2018 (23)
2007 (17)
2005 (9)
2006 (5)
2002 (3)
2004 (1)

UNIPROT ID/AC

A0A024RC46 (2)
A0A075B6P5 (2)
A0A087WT59 (2)
A0A087WTX5 (2)
A0A087WVW2 (2)
A0A087WVZ5 (2)
A0A087WXI0 (2)
A0A087WYL9 (2)
A0A087X130 (2)
A0A087X1V9 (2)
A0A0A0MS07 (2)
A0A0A0MS51 (2)
A0AVT1 (2)
A0FGR8 (2)
A0FGR8-2 (2)
A0FGR8-6 (2)
A0M8Q6 (2)
A0N5G5 (2)
A1A4S6 (2)
A1L0T0 (2)
A2BFH1 (2)
A2NB46 (2)
A2NI60 (2)
A2NUT2 (2)
A4D1S5 (2)
A4D1T9 (2)
A4F255 (2)
A5A3E0 (2)
A6NDG6 (2)
A6NDU8 (2)

ENSEMBL ID

ENSG00000170477 (2)
ENSG00000147251 (1)

CHEBI ID

CHEBI:30769 (35)
CHEBI:16919 (30)
CHEBI:15354 (29)
CHEBI:17368 (28)
CHEBI:15891 (27)
CHEBI:16704 (27)
CHEBI:17750 (25)
CHEBI:16737 (25)
CHEBI:32816 (24)
CHEBI:30915 (24)
CHEBI:17596 (24)
CHEBI:16708 (23)
CHEBI:15428 (23)
CHEBI:78320 (23)
CHEBI:18132 (22)
CHEBI:25017 (22)
CHEBI:17154 (22)
CHEBI:16449 (22)
CHEBI:18012 (22)
CHEBI:18237 (21)
CHEBI:17562 (21)
CHEBI:16750 (21)
CHEBI:28044 (21)
CHEBI:18107 (21)
CHEBI:27897 (21)
CHEBI:17775 (21)
CHEBI:17768 (20)
CHEBI:16811 (20)
CHEBI:27266 (20)
CHEBI:144829 (2)

Metabolite Name

Hypoxanthine (22)
Xanthine (21)
Creatine (20)
Choline (19)
AMP (18)
Taurine (17)
Uridine (17)
Creatinine (17)
Glutamate (15)
Lactate (15)
Betaine (15)
ADP (15)
Adenosine (15)
L-Tryptophan (15)
Alanine (14)
CMP (14)
Citrulline (14)
Ornithine (14)
UMP (14)
Pyridoxine (14)
Glycerophosphocholine (14)
Fumarate (13)
ATP (13)
Pyruvate (13)
Valine (13)
Isoleucine (13)
GMP (13)
Allantoin (13)
Pantothenic acid (13)
L-Histidine (13)

First Public Date

2025 (55)
2026 (54)
2024 (54)
2014 (32)
2023 (31)
2021 (25)
2022 (24)
2018 (22)
2020 (21)
2019 (17)
2016 (8)
2013 (7)
2017 (5)
2015 (4)

Modelling Approach

Logical model (3)
Ordinary differential equation model (2)

Study status

Completed (9)
Recruiting (8)
Terminated (3)
Not provided (3)
Active, not recruiting (1)
Withdrawn (1)

Lab affiliation

1. Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ 2. Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (CSIC), Granada, 18016, Spain (2)
1. Department I of Internal Medicine, Center for Integrated Oncology (CIO), Aachen-Bonn- Cologne-Duesseldorf, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne (UoC), 50937 Cologne, Germany 2. Department of Hematology and Cellular Therapy, University of Leipzig, Leipzig, Germany (2)
Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Campusvej 55, DK - 5230 Odense M, Denmark (2)
Mayo Clinic (2)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Associate Member Developmental Neurobiology St. Jude Children's Research Hospital (1)
Beijing Institute of Pharmacology and Toxicology (1)
CIC bioGUNE Proteomics Platform, Bizkaia Tech. Park. Build 800 (1)
Cell Signalling (1)
Children's Hospital of Philadelphia (1)
Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany (1)
Committee on Cancer Biology, The University of Chicago, Chicago, IL, USA Department of Pathology, The University of Chicago, Chicago, IL, USA Department of Pediatrics, The University of Chicago, Chicago, IL, USA The University of Chicago Medicine Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA (1)
Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215 (1)
Department of Biochemistry & Biomedicine, School of Life Sciences, University of Sussex (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (1)
Department of Chemistry and Chemical Biology, Harvard University (1)
Department of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany (1)
Division of Blood Cells and Blood Cancer The Walter and Eliza Hall Institute of Medical Research 1G Royal Parade, Parkville Victoria, Australia, 3050 (1)
Executive Director Cancer Research Group Leader, Gene Regulation Lab Peter MacCallum Cancer Centre, Parkville VIC 3052, Australia (1)
Immunology Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland (1)
Institute for Clinical Chemistry, UMM Mannheim, Germany (1)
Ist. G. Gaslini - Core Facilities - Proteomica Clinica (1)
Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical University, Hangzhou, China (1)
Laboratorio Core Facilities Gaslini Children's Hospital (1)
Laboratory Head (1)
Moffitt Cancer Center Tampa, FL, USA (1)
Prof. of Pharmacology Department of Neuroscience, Imaging and Clinical Sciences Director of Systems Pharmacology Lab, CeSI-MeT G. d’Annunzio” University, School of Medicine 66100 Chieti, Italy (1)
Professor i molekylærbiologi og faglig leder av PROMEC Institutt for klinisk og molekylær medisin Erling Skjalgssons g 1, aboratoriesenteret * * Laboratoriesenter Norwegian University of Science and Technology Trondheim 7030 Norway ( lab head ) (1)
Proteomics Lab, National Centre for Cell Science, Pune, Maharashtra, India (1)
Proteomics Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany (1)

Keyword

Fludarabine (4)
Fludarabine phosphate (4)
Mycophenolic Acid (3)
Tacrolimus (2)
Cyclosporine (2)
Cyclosporins (2)
Cyclophosphamide (2)
Pfizer SARS-CoV-2 Vaccine BNT162b2, Moderna SARS-CoV-2 Vaccine, Novavax COVID-19 Vaccine NVX-CoV2373 (1)
Circulating tumour DNA (1)
Cell-free DNA (cfDNA) (1)
Liquid biopsies (1)
Deferasirox (1)
AQ4N (1)
Diffuse (1)
Follicular (1)
Plicamycin (1)
ABCB4 Liver Toxicity (1)
ABCB11 Hepatotoxicity (1)
Metastatic Renal Cancer (1)
Transplantation (1)
Hematopoietic Stem Cell Transplantation (1)
Adult acute myeloid leukemia with del(5q) (1)
Bintrafusp Alfa M7824 (1)
NHS-IL12 M9241 (1)
PD-1(L1) (1)
Noncutaneous extranodal lymphoma (1)
Stage IA mycosis fungoides/Sezary syndrome (1)
Stage IB mycosis fungoides/Sezary syndrome (1)
Stage IIA mycosis fungoides/Sezary syndrome (1)
Stage IIB mycosis fungoides/Sezary syndrome (1)

IsPrivate

False (5)

Model Flag

Non Kinetic (2)

Submitter Keywords

Immuno-oncology (2)

Study type

Transcription profiling by array (379)
RNA-seq of coding RNA (73)
Comparative genomic hybridization by array (47)
ChIP-seq (33)
RNA-seq of coding RNA from single cells (31)
Methylation profiling by array (20)
DNA-seq (18)
Genotyping by array (13)
Unknown experiment type (9)
Methylation profiling by high throughput sequencing (9)
RNAi profiling by array (5)
ChIP-chip by tiling array (4)
MicroRNA profiling by high throughput sequencing (4)
Exome sequencing (4)
RNA-seq of total RNA (4)
Cell line - High-throughput sequencing (3)
Transcription profiling by RT-PCR (3)
Proteomic profiling by array (3)
RNA-seq of non coding RNA (3)
Animal - One-color microarray (2)
Human - High-throughput sequencing (2)
ChIP-chip by array (2)
Other (2)
MicroRNA profiling by array (2)
Transcription profiling by SAGE (1)
RNA-seq of non coding RNA from single cells (1)
MeDIP-seq (1)
Cell line - One-color microarray (1)
Spatial transcriptomics by high-throughput sequencing (1)
ATAC-seq (1)

Release Date

2022 (565)
2023 (520)
2021 (498)
2025 (464)
2020 (395)
2024 (389)
2019 (312)
2018 (274)
2017 (227)
2016 (213)
2014 (201)
2015 (191)
2013 (164)
2012 (138)
2011 (127)
2010 (102)
2026 (87)
2009 (72)
2008 (63)
2007 (26)
2006 (21)
2005 (10)
2004 (3)
2002 (3)
2001 (1)
2000 (1)

Location

United States (13)
Italy (4)
Germany (2)
Canada (2)
Japan (2)
Egypt (1)
India (1)
China (1)
Australia (1)
United Kingdom (1)

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Characterization of Whole Blood EVs Using PRotein Organic Solvent PRecipitation

Blood plays a vital role in diagnostic medicine by providing essential information for assessing health and diagnosing various conditions. Routine blood tests can reveal important biomarkers that support early diagnosis and timely intervention. Recently, extracellular vesicles (EVs) have emerged ...

2026-08-24 | MTBLS12801 | MetaboLights

A blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights

Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2782 | MetaboLights

Chromosome 11 analysis in myeloid malignancies - microarrays

blood samples from patients with myeloid malignancies were analyzed using Affymetrix Genome-Wide Human SNP 6.0 arrays.

ORGANISM(S): Homo sapiens

2013-11-01 | E-MTAB-1845 | biostudies-arrayexpress

Chromosome 11 analysis in myeloid malignancies - WES

Blood samples from patients with myeloid malignancies were analyzed using whole exome sequencing (WES). Data set from genotyping by microarray of the same samples has been deposited in ArrayExpress under accession number E-MTAB-1845 (https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-1845/).

ORGANISM(S): Homo sapiens

2013-11-01 | E-MTAB-1850 | biostudies-arrayexpress

A polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights

Global methylation alterations in Dnmt3aKO derived malignancies

To test the long-term effects of lack of Dnmt3a on mouse HSCs, we established a cohort of lethally irradiated mice transplanted with Dnmt3a-KO or WT HSC control cells. Dnmt3a deletion in purified HSCs transplanted alone leads to an array of hematologic disorders that models the spectrum of disorders...

ORGANISM(S): Mus musculus

2014-12-08 | E-GEOD-60264 | biostudies-arrayexpress

Identification of RIOK2 as a master regulator of human blood cell development

Myelodysplastic syndromes (MDS) are a group of hematologic neoplasms in which the bone marrow fails to produce enough mature blood cells, leading to peripheral blood cytopenias and myeloproliferation1-3. The average survival time following diagnosis of MDS is 2.5 years4, owing to few treatment optio...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2021-10-16 | MSV000088238 | MassIVE

Transcription profiling by array of whole blood from sickle-cell disease patients using globin mRNA reduction

Room temperature whole blood mRNA stabilization procedures, such as the PAX gene system, are critical for the application of transcriptional analysis to population-based clinical studies. Global transcriptome analysis of whole blood RNA using microarrays has proven to be challenging due to the high ...

ORGANISM(S): Homo sapiens

2009-06-20 | E-GEOD-16728 | biostudies-arrayexpress

Chromosome 11 analysis in myeloid malignancies - WES

PRJEB4555 | ENA

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