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MetabolomicsGluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei
Bloodstream form African trypanosomes are thought to rely exclusively upon glycolysis, using glucose as a substrate, for ATP production. Indeed, the pathway has long been considered a potential therapeutic target to tackle the devastating and neglected tropical diseases caused by these parasites. Ho...
2018-12-10 | MTBLS706 | MetaboLights
TranscriptomicsWild-type Lister 427 Bloodstream-form polysome profiles with ZC3H32 knock-down
Ran from polysomes of Lister 427 bloodstream forms, wild-type and a cell line with a double knockout and inducible ZC3H32, grown without tetracycline.
ORGANISM(S): Trypanosoma brucei 
2017-11-24 | E-MTAB-4558 | biostudies-arrayexpress
GenomicsRNAi against DRBD18 in Trypanosoma brucei bloodstream forms
RNAi against DRBD18 in Trypanosoma brucei bloodstream forms
PRJEB41419 | ENA
TranscriptomicsTranscriptomes from Trypanosoma brucei brucei EATRO1125 before and after differentiation of bloodstream forms to procyclic forms
Most protozoan pathogens of mammals are transmitted by invertebrate vectors and a comparison of transcriptomes of the developmental forms provides information on genes involved in interactions with different hosts. Trypanosoma brucei is the causal agent of African Trypanosomiasis and is transmitted ...
ORGANISM(S): Trypanosoma brucei brucei 
2026-07-11 | E-MTAB-17235 | biostudies-arrayexpress
GenomicsRIP-Seq of HnRNPF/H in Trypanosoma brucei bloodstream forms
RIP-Seq of HnRNPF/H in Trypanosoma brucei bloodstream forms
PRJEB46186 | ENA
GenomicsRNAi of XAC1 (Tb927.7.2780) in Trypanosoma brucei bloodstream forms
RNAi of XAC1 (Tb927.7.2780) in Trypanosoma brucei bloodstream forms
PRJEB23805 | ENA
GenomicsTranscriptomes from Trypanosoma brucei brucei EATRO1125 before and after differentiation of bloodstream forms to procyclic forms
Transcriptomes from Trypanosoma brucei brucei EATRO1125 before and after differentiation of bloodstream forms to procyclic forms
PRJEB115684 | ENA
TranscriptomicsRNAi against DRBD18 in Trypanosoma brucei bloodstream forms
RNAi against DRBD18 in Trypanosoma brucei bloodstream forms
ORGANISM(S): Trypanosoma brucei brucei 
2021-06-29 | E-MTAB-9783 | biostudies-arrayexpress
TranscriptomicsDynamic mRNA Expression analysis of cells undergoing synchronous life-cycle differentiation in Trypanosoma brucei
mRNA expression profiles of trypanosomes from two discrete bloodstream form stages of the parasite (slender and stumpy forms), as well as during the transition of the stumpy population to the procyclic life-cycle stage were studied. Our analysis represents the first comparison of in vivo derived ple...
ORGANISM(S): Trypanosoma brucei 
2010-05-16 | E-GEOD-17026 | biostudies-arrayexpress
TranscriptomicsRegulation of Trypanosoma brucei total and polysomal mRNA during development within its mammalian host
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly. However, trypanosomes also undergo development within the mammalian bloodstream as they progress from morphologically M-bM...
ORGANISM(S): Trypanosoma brucei brucei 
2013-12-16 | E-GEOD-46388 | biostudies-arrayexpress
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