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Genomicsena-DATASET-STSI-01-02-2018-19:27:28:627-506 - samples
Whole-Genome Sequencing of a Healthy Aging Cohort.
EGAD00001003941 | EGA
GenomicsWellderly Study
Data Access Committee EGAC00001000663
EGAC00001000663 | EGA
GenomicsWhole-Genome Sequencing of a Healthy Aging Cohort.
Studies of long-lived individuals have revealed few genetic mechanisms for protection against age-associated disease. Therefore, we pursued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free aging without medical intervention. In contrast with studies o...
EGAS00001002306 | EGA
TranscriptomicsRNA-seq and genome-wide CRISPRi and Tn-seq analyses of BVL3572S-treated Mycobacterium tuberculosis H37Rv
(i) RNA-seq of M. tuberculosis H37Rv cultures grown in the presence of BVL3572S for 6 h compared to untreated controls. (ii) Genome-wide M. tuberculosis H37Rv CRISPRi libraries were grown in the presence of ATc for 5 days prior to drug exposure. Cultures were treated with sub-MIC BVL3572S concentra...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2026-04-20 | E-MTAB-16773 | biostudies-arrayexpress
TranscriptomicsNovel Observations from Next Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets
Understanding distinct gene expression patterns of normal adult and developing fetal human pancreatic a and b cells is crucial for developing stem cell therapies, islet regeneration strategies, and therapies designed to increase b cell function in patients with diabetes (type 1 or 2). Toward that en...
ORGANISM(S): Homo sapiens 
2015-06-08 | E-GEOD-67543 | biostudies-arrayexpress
TranscriptomicsAnalysis of ethanologenic E.coli strain GLBRCE1 during fermentation of alkaline-pretreated corn stover hydrolysate
The physiology of ethanologenic Escherichia coli grown anaerobically in alkaline-pretreated plant hydrolysates is not well studied. To gain insight into how E. coli responds to such hydrolysates, we studied an E. coli K-12 ethanologen fermenting a hydrolysate prepared from corn stover pre-treated by...
ORGANISM(S): Escherichia coli 
2012-06-17 | E-GEOD-35049 | biostudies-arrayexpress
TranscriptomicsTP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
Background: Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical care. The aim of this study was to evaluate the prognostic value of gene expression-based classification along with established prog...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-40954 | biostudies-arrayexpress
TranscriptomicsMicroarray expression analysis of Drosophila DrosDel deficiency lines
Microarray data of DrosDel deficiency (Df/+) and parental strain diploid flies along with spike-in controls was performed on the Nimblegen 12-plex array platform. Samples are named in this dataset according to the following sample naming scheme: tissue_genotype shorthand_sex_biological replicate #. ...
ORGANISM(S): Drosophila melanogaster 
2012-04-02 | E-GEOD-31386 | biostudies-arrayexpress
TranscriptomicsDrosophila DrosDel deficiency and diploid control flies
GSE31386: Microarray expression analysis of Drosophila DrosDel deficiency lines GSE31401:RNA-Seq on SOLiD platform of DrosDel deficiency and w1118 flies GSE31549: RNA-Seq on Illumnia platform of DrosDel deficiency and w1118 lines GSE31550: DNA-Seq of Drosophila DrosDel deficiency and w1118 lines Ref...
ORGANISM(S): Drosophila melanogaster 
2012-04-02 | E-GEOD-31407 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 25 Coxiella burnetii isolates relative to the Nine Mile (RSA493) reference isolate
Analysis of genetic diversity of 25 Coxiella burnetii isolates with relative to the Nine Mile (RSA493) reference isolate.
ORGANISM(S): Coxiella burnetii 
2006-10-30 | E-TABM-35 | biostudies-arrayexpress
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