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GenomicsUltra-resolution, multiscale live imaging reveals TADs as domains of cohesin-accelerated search
Ultra-resolution, multiscale live imaging reveals TADs as domains of cohesin-accelerated search
PRJNA1223449 | ENA
TranscriptomicsKnockdown of Polyhomeotic in Drosophila Kc cells
In this experiment, we used RNAi targeting both copies of the gene polyhomeotic (ph-p and ph-d) to knockdown expression of this factor in Drosophila Kc167 cells. We observed substantial changes to the structure of genomic loci bound by Polycomb-group proteins as assayed by single-molecule based sup...
ORGANISM(S): Drosophila melanogaster 
2015-11-20 | E-GEOD-75060 | biostudies-arrayexpress
TranscriptomicsSpatially resolved, highly multiplexed RNA profiling in single cells
Knowledge of the expression profile and spatial landscape of the transcriptome in individual cells is essential for understanding the rich repertoire of cellular behaviors. Here we report multiplexed error-robust fluorescence in situ hybridization (MERFISH), a single-molecule imaging approach that a...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-67685 | biostudies-arrayexpress
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