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TranscriptomicsIn vitro and in vivo evidences of osteocytes involvement in myeloma-induced osteoclast formation and bone disease
The involvement of osteocytes in multiple myeloma (MM)-induced osteoclast formation and the occurrence of bone lesions are still unknown. Osteocytes regulate bone remodeling at least in part through the cell death and apoptosis triggering osteoclast recruitment and formation. In this study, firstly ...
ORGANISM(S): Homo sapiens 
2012-05-21 | E-GEOD-27372 | biostudies-arrayexpress
TranscriptomicsBone Marrow Monocyte/Macrophage Derived Activin A Mediates the Osteoclastogenic Effects of IL-3 in Myeloma
Myeloma bone disease is characterized by tremendous bone destruction with suppressed bone formation. IL-3 is a multifunctional cytokine that increases myeloma cell growth and osteoclast proliferation while inhibiting osteoblast differentiation. While IL-3 appears to be an attractive therapeutic targ...
ORGANISM(S): Homo sapiens 
2014-11-01 | E-GEOD-41992 | biostudies-arrayexpress
UnknownInside Mycobacterium bovis SB0120 spoligotype circulating in Italy: analysis of the most frequent genotypes by whole genome sequencing.
Not available
S-EPMC11310128 | biostudies-literature
UnknownProcessing-Dependent and Clonal Contamination Patterns of Listeria monocytogenes in the Cured Ham Food Chain Revealed by Genetic Analysis.
Not available
S-EPMC4725272 | biostudies-literature
UnknownSalmonella Derby adaptation to swine and simultaneous attenuation for humans go through decay of Salmonella Pathogenicity Island I.
Not available
S-EPMC10715017 | biostudies-literature
UnknownHigh-resolution diffusion pattern of human infections by Salmonella enterica serovar Napoli in Northern Italy explained through phylogeography.
Not available
S-EPMC6104998 | biostudies-literature
UnknownRise and fall of outbreak-specific clone inside endemic pulsotype of Salmonella 4,[5],12:i:-; insights from high-resolution molecular surveillance in Emilia-Romagna, Italy, 2012 to 2015.
Not available
S-EPMC5883454 | biostudies-literature
UnknownEstimation of Mycobacterium avium subsp. paratuberculosis load in raw bulk tank milk in Emilia-Romagna Region (Italy) by qPCR.
Not available
S-EPMC4985589 | biostudies-literature
UnknownKlebsiella pneumoniae carrying multiple alleles of antigen 43-encoding gene of Escherichia coli associated with biofilm formation.
Not available
S-EPMC9899198 | biostudies-literature
UnknownDifferential single nucleotide polymorphism-based analysis of an outbreak caused by Salmonella enterica serovar Manhattan reveals epidemiological details missed by standard pulsed-field gel electrophoresis.
Not available
S-EPMC4365250 | biostudies-literature
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