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The endogenous cellular prion protein (PrPC) can misfold into the scrapie isoform (PrPSc) and cause fatal infectious diseases. Despite significant research on the prion protein, both its normal function and whether alterations to that function play a critical role in prion diseases remain unknown. T...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-16 | PXD012427 | Pride
In the malaria parasite Plasmodium falciparum, epigenetic modifications such as acetylation and methylation play important roles in parasite biology and virulence. Here, we characterised a new epigenetic mark, histone lactylation, recently discovered in humans and also present in Plasmodium. It was ...
ORGANISM(S): Plasmodium knowlesi strain H Plasmodium falciparum NF54 
2025-12-15 | PXD055236 | Pride
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