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MetabolomicsQuantitative profiling of endocannabinoids in lipoproteins by LC–MS/MS
Endocannabinoids belong to a diverse family of endogenous lipid bioregulators acting as physiological ligands of cannabinoid receptor type 1 and cannabinoid receptor type 2 in the central and peripheral nervous system. They are also present in nmol/l concentrations in human blood plasma; however, th...
2015-03-11 | MTBLS163 | MetaboLights
UnknownAdjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: restoration of previously unpublished methodology.
Not available
S-EPMC7691700 | biostudies-literature
MetabolomicsBenthic exometabolites and their ecological significance on threatened Caribbean coral reefs (Metabolite collection incubation assays)

Benthic organisms sustain coral reefs through their growth and metabolism, but less is known about how their released metabolites influence reef seawater microorganisms. To investigate metabolite composition of benthic exudates and their ecological significance for reef microbial communities, we ...

2022-08-22 | MTBLS2855 | MetaboLights
ProteomicsStructuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery
Lipid nanoparticles (LNPs) play a crucial role in addressing genetic disorders, and cancer, and combating pandemics such as COVID-19 and its variants. Yet, in contrast remarkable achievements in siRNA and mRNA delivery, the ability of LNPs to effectively encapsulate large-size DNA molecules remains ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-02 | PXD054751 | Pride
Protein corona Lipid nanoparticles Dna 
ProteomicsMETAPROTEOMIC INVESTIGATION OF BIOAEROSOL FROM WORK ENVIRONMENTS
Metaproteomic analysis of air particulate matter provides information about the properties of bioaerosols in the atmosphere and their influence on climate and public health. In this work, a new method for the extraction and analysis of proteins in airborne particulate matter from quartz microfiber ...
ORGANISM(S): Candida albicans (Yeast) Triticum aestivum (Wheat) Escherichia coli Oryza sativa (Rice) 
2025-07-14 | PXD012345 | Pride
Bioaereosol  metaproteomics  extraction methods  composting plant  wastewater treatment plant  agricultural holding  high resolution mass spectrometry 
MetabolomicsAdvancing Reef Monitoring Techniques through Exometabolomics: Quantification of Labile Dissolved Organic Metabolites on Coral Reefs

Extracellular chemical cues constitute much of the language of life among marine organisms from microbes to mammals. These chemical cues shape foraging and feeding strategies, symbiotic interactions, selection of mates and habitats, and the transfer of energy and nutrient...

2025-07-16 | MTBLS9008 | MetaboLights
ProteomicsPlatelet Proteomics to Understand the Pathophysiology of Immune Thrombocytopenia: Studies in Mouse Models
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by enhanced platelet clearance and defective platelet production. Diagnosis by exclusion and “trial-error” treatment strategies are common practice, and despite the advancement conferred by Thrombopoietin receptor agonists (TPO-RA´...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD028814 | Pride
Immune thrombocytopenia Platelets Pre-clinical mouse models Bottom-up proteomics 
TranscriptomicsMicroarray analysis of breast cancer cell lines with different levels of P-cadherin expression treated with the anti-cancer bacterial protein azurin
We performed a microarray analysis to compare the expression profile of azurin treated and untreated with different P-cadherin expression levels. We also compared the differentially expressed genes regulated by P-cadherin overexpression. Both cell lines presented an up-regulation of apoptosis mediat...
ORGANISM(S): Homo sapiens 
2014-04-30 | E-GEOD-54319 | biostudies-arrayexpress
ProteomicsPresentation of the Extra-Cellular Domain of the Sars2 Spike Glycoprotein by Immunopeptidomic Profiling of HLA-II Bound Peptides from Human Dendritic Cells
In the present study we sought to identify the naturally processed and presented immunopeptidome of the SARS-CoV-2 spike glycoprotein from human antigen presenting cells. Monocyte-derived dendritic cells from a panel of healthy human subjects representing a majority of the HLA-DRB1 allele usage with...
ORGANISM(S): Sars Coronavirus (ncbitaxon:227859) Bos (ncbitaxon:9903) Homo Sapiens (ncbitaxon:9606) 
2020-05-21 | MSV000085456 | MassIVE
UnknownBaricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
Not available
S-EPMC9333998 | biostudies-literature
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