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TranscriptomicsAndrogen Regulated Genes in Intact Human Prostate Tissues: Relation to Benign Prostatic Hyperplasia and Prostate Cancer
To investigate gene expression profiling in intact human prostate tissue xenografts in mice, following the addition or subtraction of androgens. 58 prostate samples were implanted into castrated or testosterone-treated mice for 5 different lengths of time. Samples were compared to a control pool cre...
ORGANISM(S): Homo sapiens 
2010-06-14 | E-GEOD-17862 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hippocampal neuronal cell line HT-22 after 7 days of 3mM Lithium treatment
Effect of 3 mM lithium on gene's expression in mouse hippocampal neuronal cell line HT-22 after 7 days of treatment
ORGANISM(S): Mus musculus 
2006-02-01 | E-MEXP-521 | biostudies-arrayexpress
TranscriptomicsC/EBPbeta-2 regulation of gene expression in MCF10A cells
C/EBPbeta-2 results in EMT and ErbB indpendence this project investigated the gene changes in related genes upon C/EBPbeta-2 overexpression in MCF10A cells. We used microarray analysis to detail the global gene expression mediated by C/EBPbeta-2 and identified changes in known EMT genes, however, k...
ORGANISM(S): Homo sapiens 
2010-03-06 | E-GEOD-15065 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis on Salt Stress Affected Genes in Tomato Seedlings
Large-scale gene expression affected by salt stress was analyzed with tomato seedlings (Lycoperson esculentum Mill cv. Money Maker) by a cDNA microarray (Tom1). The significantly differentially expressed genes (5% Benjamini-Hochberg false discovery rate) consisted of 1757 sequences in the analyzed...
ORGANISM(S): Solanum lycopersicum 
2007-09-04 | E-GEOD-8883 | biostudies-arrayexpress
TranscriptomicsDisruption of PPARg signaling results in mouse prostatic intraepithelial neoplasia (mPIN) involving active autophagy
Peroxisome proliferator-activated receptor-gamma (PPARg) regulates the interface between cellular lipid metabolism, redox status and organelle differentiation. Following conditional prostatic epithelial knockout of PPARg in mice we observed focal hyperplasia of the epithelium which developed to mous...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-13867 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles in Thermally Injured Human Skin: A Temporal Microarray Analysis
Thermal injury incites inflammatory responses that often transcend the local environment and lead to structural deficiencies in skin that give way to scar formation. We hypothesized that extensive perturbations within burned skin following thermal insult and during subsequent events of wound repair ...
ORGANISM(S): Homo sapiens 
2010-05-22 | E-GEOD-8056 | biostudies-arrayexpress
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