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ProteomicsMatrisome age-related changes in the mouse gastrocnemius muscle
In recent years, thanks to the great development of mass spectrometry (MS)-based high-throughput proteomic techniques, a large-scale protein characterization is less challenging. Proteomic approaches have been successfully applied to SM in different experimental models [21–24]; however, to date, the...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD027895 | Pride
Aging  extracellular matrix  proteomics  ultrastructure  skeletal muscle  sarcopenia 
ProteomicsMitochondrial structure and bioenergetics in Pseudoxanthoma elasticum
Aim of the present study was to integrate structural and bioenergenetic features to deeply investigate mitochondria of control and of PXE fibroblasts cultured in standard conditions, to explore their role in the development of the fibroblasts’ pathologic phenotype.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD021647 | Pride
Mitochondria Fibroblast Pxe Proteome Ultrastructure 
ProteomicsPomacea canaliculata ampullar proteome: a nematode-based bio-pesticide induces changes in metabolic and stress-related pathways
Recent pandemic outbreaks confirmed the crucial role of early detection and more comprehensive knowledge of invasive species and infectious diseases. The freshwater snail Pomacea canaliculata is indexed among the most invasive pests in the world and it can be the intermediate host of the human paras...
ORGANISM(S): Pomacea canaliculata 
2022-02-17 | PXD026801 | Pride
Amupulla Qexactive Biopesticide Pomacea canaliculata 
ProteomicsFibroblasts’ secretome from calcified and non-calcified dermis in Pseudoxanthoma elasticum differently contributes to elastin calcification.
Pseudoxanthoma elasticum (PXE) is characterized by ectopic calcification, however, despite the widely spread effect of pro/anti-calcifying systemic factors associated with the genetic metabolic condition, it not known why elastic fibers (EF) in the same patient are mainly fragmented or highly minera...
ORGANISM(S): Homo sapiens (Human) 
2024-04-18 | PXD048829 | Pride
Fibroblasts  elastin  mineralization  proteomics  pxe 
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