A long intergenic non-protein-coding RNA , BORG, is almost exclusively expressed in neurons and is induced during the differentiation of human and mouse pluripotent cells and neuronal progenitors into neurons. shRNA knockdown was used to examine the effects of BORG expression
A long intergenic non-protein-coding RNA , BORG, is almost exclusively expressed in neurons and is induced during the differentiation of human and mouse pluripotent cells and neuronal progenitors into neurons.
The ubiquitous nature of lncRNAs to comprehensively alter cellular transcriptional networks led us to hypothesize that BORG is capable of compelling metastasic, chemoresistant, and pro-survival activities in triple-negative breast cancers by inducing global transcriptomic reprogramming. As such, we ...
