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TranscriptomicsTat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNAs by HIV-1
Herein expression trends of host miRNA were measured in CEMx174 lymphocytes infected with HIV-1NL4-3 or derivative strains deficient in Tat RSS activity (RSS) or vif-/vpr (VV), or unexposed to virus. As expected from previous studies, miRNA trends were different in naive and HIV-1 infected cells. ...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-21892 | biostudies-arrayexpress
TranscriptomicsIdentification of transcripts regulated by RNA helicase A (RHA)
This SuperSeries is composed of the following subset Series: GSE14055: Changes in polysome loading as a consequence of RHA downregulation GSE14056: Co-immunoprecipitation of RNAs with RNA helicase A (RHA) Refer to individual Series
ORGANISM(S): Chlorocebus aethiops 
2008-12-19 | E-GEOD-14057 | biostudies-arrayexpress
TranscriptomicsCo-immunoprecipitation of RNAs with RNA helicase A (RHA)
Given that RHA regulates translation by binding a PCE located at the 5’ UTR of the target transcripts a genome-wide screen was performed to identify mRNAs that bind RHA in vivo. The results from duplicate experiments with samples obtained in two independent RNA immunoprecipitations identified 407 tr...
ORGANISM(S): Chlorocebus aethiops 
2008-12-19 | E-GEOD-14056 | biostudies-arrayexpress
TranscriptomicsChanges in polysome loading as a consequence of RHA downregulation
RNA helicase A (RHA) binds its target transcripts at the post-transcriptional control element (PCE) located in the 5â?? untranslated region (UTR). This interaction represents an â??RNA switchâ?? that regulates protein synthesis. Down regulation of RHA by siRNAs was used to identify transcripts with ...
ORGANISM(S): Chlorocebus aethiops 
2010-05-15 | E-GEOD-14055 | biostudies-arrayexpress
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