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TranscriptomicsFactor VII activating protease (FSAP) exerts antifibrotic effects in a mouse model of experimental liver fibrosis
Background and Rationale: Factor VII activating protease (FSAP) is a circulating serine protease produced in the liver. A single nucleotide polymorphism (G534E, Marburg I, MI-SNP) in the gene encoding FSAP (HABP2) leads to lower enzymatic activity and is associated with enhanced liver fibrosis. FSAP...
ORGANISM(S): Mus musculus 
2012-09-19 | E-GEOD-36066 | biostudies-arrayexpress
TranscriptomicsTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Death receptor-mediated hepatocyte apoptosis is implicated in a wide range of liver diseases including viral hepatitis, alcoholic hepatitis, ischemia/reperfusion injury, fulminant hepatic failure, cholestatic liver injury and cancer. Deletion of NF-ĸB essential modulator in hepatocytes (NemoΔhepa) c...
ORGANISM(S): Mus musculus 
2014-09-03 | E-GEOD-33161 | biostudies-arrayexpress
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