Sort   by:  
 Page size 
TranscriptomicsSaturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine
We studied the effect of dietary fat type, varying in polyunsaturated/saturated fatty acid ratio's (P/S) on development of metabolic syndrome. C57Bl/6J mice were fed purified high-fat diets (45E% fat) containing palm oil (HF-PO; P/S 0.4), olive oil (HF-OO; P/S 1.1) or safflower oil (HF-SO; P/S 7.8) ...
ORGANISM(S): Mus musculus 
2012-06-17 | E-GEOD-18586 | biostudies-arrayexpress
UnknownA Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones.
Not available
S-EPMC6385050 | biostudies-literature
TranscriptomicsSupplementary dietary calcium stimulates faecal fat and bile acid excretion, but does not protect against obesity and insulin resistance in C57BL/6J mice
There is increased interest in the potential protective role of dietary Ca in the development of metabolic disorders related to the metabolic syndrome. Ca-induced intestinal precipitation of fatty acids and bile acids as well as systemic metabolic effects of Ca on adipose tissue is proposed to play ...
ORGANISM(S): Mus musculus 
2011-03-03 | E-GEOD-18581 | biostudies-arrayexpress
TranscriptomicsResistant starch induces catabolic but suppresses immune and cell division pathways and changes the microbiome in proximal colon of male pigs
Consumption of resistant starch (RS) has been associated with various intestinal health benefits, but knowledge on its effects on global gene expression in the colon is limited. The main objective of the current study was to identify genes affected by RS in the proximal colon to infer which biologic...
ORGANISM(S): Sus scrofa 
2013-10-18 | E-GEOD-45554 | biostudies-arrayexpress
ProteomicsMS analysis of photocrosslink adducts for the mapping of interaction sites of selective engineered PSD-95 PDZ domain ligands
Designing highly specific modulators of protein-protein interactions (PPIs) is especially challenging in the context of multiple paralogs and conserved interaction surfaces. In this case, direct generation of selective and competitive inhibitors is hindered by high similarity within the evolutionary...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-12 | PXD015366 | Pride
Engineered ligand/pdz domains/photocrosslinking/p-azidophenylalanine 
UnknownImpact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.
Not available
S-EPMC5455690 | biostudies-literature
UnknownmiR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Not available
S-EPMC6010451 | biostudies-literature
UnknownRespiratory Dysfunction and Abnormal Hypoxic Ventilatory Response in Mild to Moderate Parkinson's Disease.
Not available
S-EPMC11647984 | biostudies-literature
TranscriptomicsTranscription profiling of mouse PPARalpha knockouse to investigate TPPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression
Background: The selective absorption of nutrients and other food constituents in the small intestine is mediated by a group of transport proteins and metabolic enzymes, often collectively called ‘intestinal barrier proteins’. An important receptor that mediates the effects of dietary lipids on g...
ORGANISM(S): Mus musculus 
2008-06-18 | E-GEOD-9533 | biostudies-arrayexpress
UnknownFive seconds to safety: detecting and managing critical instability before structured handover in non-trauma patients.
Not available
S-EPMC12849088 | biostudies-literature
Sort   by:  
 Page size