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TranscriptomicsGenome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs
MicroRNAs (miRNAs) are a large family of 19-22nt non-coding RNAs that post-transcriptionally regulate their mRNA targets. Computational algorithms predict that over half of all genes are regulated by miRNAs, yet approaches for experimental identification of miRNA binding sites are now emerging. To ...
ORGANISM(S): Mus musculus 
2011-01-10 | E-GEOD-25310 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [Exon array]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44161 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44163 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [small_RNA-Seq]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44156 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [CLIP-Seq]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-45828 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [RNA-seq_siRNA_transfection]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44157 | biostudies-arrayexpress
GenomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [ChIP-seq_histone]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44159 | biostudies-arrayexpress
GenomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [ChIP-seq_nr6a1]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44160 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [3p arrays]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44162 | biostudies-arrayexpress
TranscriptomicsLet-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [mRNA-seq_Flag-HA-NR6A1_overexpr]
MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with incr...
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-44158 | biostudies-arrayexpress
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