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MetabolomicsA Multi-Omics Analysis of Glycine max Leaves Reveals Alteration in Flavonoid and Isoflavonoid Metabolism Upon Ethylene and Abscisic Acid Treatment
Phytohormones are central to plant growth and development. Despite the advancement in our knowledge of hormone signaling, downstream targets, and their interactions upon hormones action remain largely fragmented, especially at the protein and metabolite levels. With an aim to get new insight into th...
2018-09-20 | MTBLS531 | MetaboLights
MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
TranscriptomicsIdentification of MAX signature on MAX deficient SCLC cell lines
To development our gene expression approach, we have employed whole genome microarray expression profiling as a discovery platform to identify genes potentialy regulated by the transcription factor MAX.Human SCLC cell lines waere analyzed for mutations at the MAX locus. Those cell lines that were f...
ORGANISM(S): Homo sapiens 
2013-12-28 | E-GEOD-48559 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of Glycine max Cotyledons and Trifoliate Leaves to Determine Genes Associated with Senescence
We use RNA sequencing technology in a time course study to measure transcript abundance from three developmental stages in cotyledons and five stages in the trifoliate leaf of Glycine max to identify genes with distinct temporal patterns of expression during leaf or cotyledon development. We also ex...
ORGANISM(S): Glycine max 
2015-05-01 | E-GEOD-61857 | biostudies-arrayexpress
TranscriptomicsRNA-Seq Profiling of a Defective Seed Coat Mutation in Glycine max Reveals Differential Expression of Proline Rich and Other Cell Wall Protein Transcripts
The plant cell wall performs a number of essential functions including providing shape to many different cell types and serving as a defense against potential pathogens. The net pattern mutation creates breaks in the seed coat of soybean (Glycine max) because of ruptured cell walls. Using RNA-Seq, w...
ORGANISM(S): Glycine max 
2014-05-16 | E-GEOD-54903 | biostudies-arrayexpress
TranscriptomicsIdentification of soybean seed developmental stage specific and tissue specific miRNA targets by degradome sequencing .
Five degradome libraries were constructed from three different seed developmental stages. Separate degradome libraries were constructed for seed coat and cotyledons to identify the tissue specific miRNAs and their potential targets. Sequencing and analysis of degradome libraries gives identification...
ORGANISM(S): Glycine max 
2012-08-07 | E-GEOD-34433 | biostudies-arrayexpress
TranscriptomicsTranscriptional Analysis of 1M Regions in Glycine max Using Tiling Microarrays
We report here a transcriptonal analysis in six different organ types of a approximately 1 Mb region in soybean (Glycine max) which is sytenic with legume (Medicago truncatula). We used oligonucleotide tiling microarrays to detecte transcription of over 80% of the predicted genes in both species. We...
ORGANISM(S): Glycine max 
2010-05-26 | E-GEOD-10056 | biostudies-arrayexpress
TranscriptomicsTranscriptional Analysis of Medicago truncatula and Glycine max Using Tiling Microarrays
This SuperSeries is composed of the following subset Series: GSE10055: Transcriptional Analysis of 1M Regions in Medicago truncatula Using Tiling Microarrays GSE10056: Transcriptional Analysis of 1M Regions in Glycine max Using Tiling Microarrays Keywords: tiling array, transcriptional analysis Both...
ORGANISM(S): Glycine max 
2010-05-26 | E-GEOD-10151 | biostudies-arrayexpress
ProteomicsMAX-mutant small cell lung cancers exhibit impaired activities of MGA-dependent ncPRC1.6.
The MYC axis is commonly disrupted in cancer, mostly by activation of the MYC family of oncogenes, but also by genetic inactivation of MAX, the obligate partner of MYC, and of the MAX partner, MGA, both of which are members of the polycomb repressive complex, ncPRC1.6. While the oncogenic properties...
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD017658 | Pride
Max-gene associated protein Proteomics Cell lung cancer Mga Immunoprecipitation Max 
TranscriptomicsComprehensive characterization and RNA-Seq profiling of the HD-Zip transcription factor family in soybean (Glycine max) during dehydration and salt stress
Background The homeodomain leucine zipper (HD-Zip) transcription factor family is one of the largest plant specific superfamilies, and includes genes with roles in modulation of plant growth and response to environmental stresses. Many HD-Zip genes are characterized in Arabidopsis (Arabidopsis thal...
ORGANISM(S): Glycine max 
2014-11-01 | E-GEOD-57252 | biostudies-arrayexpress
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