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ProteomicsMGA interactome in 293T cells using affinity purification and mass spectrometry
Tandem affinity purification of MGA-interacting proteins and mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2021-07-06 | PXD025930 | Pride
Mga Immunoprecipitation Interactome Lc-ms/ms 
ProteomicsMAX-mutant small cell lung cancers exhibit impaired activities of MGA-dependent ncPRC1.6.
The MYC axis is commonly disrupted in cancer, mostly by activation of the MYC family of oncogenes, but also by genetic inactivation of MAX, the obligate partner of MYC, and of the MAX partner, MGA, both of which are members of the polycomb repressive complex, ncPRC1.6. While the oncogenic properties...
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD017658 | Pride
Max-gene associated protein Proteomics Cell lung cancer Mga Immunoprecipitation Max 
TranscriptomicsPhosphorylation events in the Multiple Gene Regulator of Group A Streptococcus (Mga) Significantly Influences Global Gene Expression and Virulence.
We sought understand the molecular mehcanism of gene regulation by Mga and its contribution to GAS pathogenesis in serotype M59 GAS through whole transcriptome analysis of strains with phosphorylation mimicking substitutions in key histidine residues of Mga. There were 6 strains analyzed, each in tr...
ORGANISM(S): Streptococcus pyogenes MGAS15252 
2015-04-18 | E-GEOD-67988 | biostudies-arrayexpress
TranscriptomicsM6 Mga+ vs Mga-
The transcriptional regulator Mga of Streptococcus pyogenes (the group A streptococcus, GAS) is known to directly activate several virulence genes important for colonization and immune evasion during exponential growth. Transcriptome analysis comparing two mga-1 serotypes (M1 SF370, M6 JRS4) and one...
ORGANISM(S): Streptococcus pyogenes 
2006-08-31 | GSE4598 | GEO
TranscriptomicsM4 Mga+ vs Mga-
The transcriptional regulator Mga of Streptococcus pyogenes (the group A streptococcus, GAS) is known to directly activate several virulence genes important for colonization and immune evasion during exponential growth. Transcriptome analysis comparing two mga-1 serotypes (M1 SF370, M6 JRS4) and one...
ORGANISM(S): Streptococcus pyogenes 
2006-08-31 | GSE4597 | GEO
TranscriptomicsM1 Mga+ vs Mga-
The transcriptional regulator Mga of Streptococcus pyogenes (the group A streptococcus, GAS) is known to directly activate several virulence genes important for colonization and immune evasion during exponential growth. Transcriptome analysis comparing two mga-1 serotypes (M1 SF370, M6 JRS4) and one...
ORGANISM(S): Streptococcus pyogenes 
2006-08-31 | GSE4596 | GEO
GenomicsMga
Mga
PRJNA1050289 | ENA
GenomicsMGA represses MYC-target genes [ChIP-seq]
MGA represses MYC-target genes [ChIP-seq]
PRJNA445195 | ENA
GenomicsMGA represses MYC-target genes [RNA-seq]
MGA represses MYC-target genes [RNA-seq]
PRJNA445194 | ENA
TranscriptomicsRNA-seq of four human glioblastoma cell lines from heterogeneous U-343 cell system
Four glioblastoma cell line U-343 MG, U-343 MGa, U-343 MGa 31L, U-343 MGa Cl2:6 were derived form the same glioblastoma U-343. The RNA-seq was performed to identify their difference and better understand the glioblastoma heterogeneity.
ORGANISM(S): Homo sapiens 
2020-08-10 | E-MTAB-8620 | biostudies-arrayexpress
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