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TranscriptomicsA Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma actively remodels the transcriptome of its hosting cells with profound and coupled impact on the host immune response. ...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-38782 | biostudies-arrayexpress
TranscriptomicsDrug-inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites
Plasmodium and Toxoplasma are parasites of major medical importance that belong to the Apicomplexa phylum of protozoa. These parasites transform into various stages during their life cycle and express a specific set of proteins at each stage. Although still little is known of how gene expression is ...
ORGANISM(S): Toxoplasma gondii 
2010-06-21 | E-GEOD-15241 | biostudies-arrayexpress
ProteomicsTgondii - Whole organism, iBAQ (Farhatetal,natmicrobiol2020)
abundance based on iBAQ, Interaction consistency score: 12.1, Coverage: 30
ORGANISM(S): 5811 
2020-00-00 | 2851512285 | PAXDB
TranscriptomicsHost cell subversion by Toxoplasma GRA16, a HAUSP- and PP2A-interacting protein exported to the host cell nucleus
Toxoplasma gondii multiplies inside a parasitophorous vacuole in the host cell. Several parasite proteins have been described that hijack host signaling pathways, which mostly originate from the rhoptry organelles. We report here the identification and characterization of GRA16, the first dense gran...
ORGANISM(S): Homo sapiens 
2013-02-06 | E-GEOD-38779 | biostudies-arrayexpress
UnknownUncovering Biomarkers for Chronic Toxoplasmosis Detection Highlights Alternative Pathways Shaping Parasite Dormancy
Not available
S-SCDT-10_1038-S44321-025-00252-0 | biostudies-other
TranscriptomicsToxoplasma TgIST co-opts Host Chromatin Repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses
An early hallmark of Toxoplasma infection is the rapid control of the parasite population by a potent multifaceted innate immune response that engages resident and homing immune cells along with pro- and counter-inflammatory cytokines. In this context, IFN-γ activates a variety of Toxoplasma-target...
ORGANISM(S): Homo sapiens 
2016-07-18 | E-GEOD-81613 | biostudies-arrayexpress
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