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TranscriptomicsMicro-RNAs levels in wildtype vs. Ahr-null adult mouse liver constitutively and in response to doxin treatment.
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Mus musculus 
2007-08-14 | E-GEOD-8468 | biostudies-arrayexpress
TranscriptomicsNanoString analysis of a rat liver mRNA panel following TCDD treatment
Profiling of mRNA abundances with high-throughput platforms such as microarrays and RNA-Seq has become an important tool in both basic and biomedical research. However these platforms remain prone to systematic errors, and have challenges in clinical and industrial application. As a result it is sta...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-43251 | biostudies-arrayexpress
UnknownFeature-level exploration of a published Affymetrix GeneChip control dataset.
Not available
S-EPMC1779590 | biostudies-literature
UnknownA reanalysis of a published Affymetrix GeneChip control dataset.
Not available
S-EPMC1557755 | biostudies-literature
TranscriptomicsMicro-RNAs in Adult Long-Evans (Turku/AB) Rat Liver are Refractory to 96 Hours Dioxin Treatment
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-14 | E-GEOD-8469 | biostudies-arrayexpress
TranscriptomicsMale and Female Mice Show Significant Temporal Differences in Hepatic Transcriptomic Response to TCDD
2,3,7,8M-bM-^@M-^Stetrachlorodibenzo-p-dixion (TCDD) is a dioxin congener that causes a wide range of toxic effects in rodent species. Previous studies discovered that males and females of the same species display different sensitivities to TCDD exposure. Although it is now clear that most TCDD-indu...
ORGANISM(S): Mus musculus 
2015-03-01 | E-GEOD-61038 | biostudies-arrayexpress
UnknownValection: design optimization for validation and verification studies.
Not available
S-EPMC6157051 | biostudies-literature
TranscriptomicscirDNA methylome analysis in prostate cancer
DNA modification profiling of circulating DNA (cirDNA) from plasma samples from prostate cancer patients (T2-3N0Mx), benign prostatic hyperplasia and control individuals Epigenetic differences are a common feature of many diseases, including cancer, and disease-associated changes have even been dete...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-36195 | biostudies-arrayexpress
ProteomicsCLDN3 in prostate cancer exosomes
Exosomes are an emerging source for biomarkers in various diseases. Prostate cancer is the most frequent cancer in men in industrialized countries. The only biomarker widely used is prostate specific antigen with its clinical relevance suffering from low specificity. To identify novel biomarker cand...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2017-04-13 | PXD003651 | Pride
Claudin3 Mass spectrometry Exosomes Prostate cancer 
TranscriptomicsTranscription profiling of mouse liver from wild-type or genetically deleted AHRs were treated with corn oil vehicle or TCDD reveals aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
Conventional biochemical and molecular techniques identified previously several genes whose expression is regulated by the aryl hydrocarbon receptor (AHR). We sought to map the complete spectrum of AHR-dependent genes in male adult liver using expression arrays to contrast mRNA profiles in Ahr-null ...
ORGANISM(S): Mus musculus 
2008-11-13 | E-GEOD-10082 | biostudies-arrayexpress
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