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TranscriptomicsHigh-resolution chromosomal maps of Xist RNA reveal a two-step spreading mechanism during X-inactivation
The Xist long noncoding RNA (lncRNA) is essential for X-chromosome inactivation (XCI), the process by which mammals compensate for unequal numbers of sex chromosomes. During XCI, Xist coats the future inactive X (Xi) and recruits Polycomb Repressive Complex 2 (PRC2) to the X-inactivation center (Xic...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-48649 | biostudies-arrayexpress
UnknownAdditional copies of the proteolipid protein gene causing Pelizaeus-Merzbacher disease arise by separate integration into the X chromosome.
Not available
S-EPMC1287072 | biostudies-literature
TranscriptomicsA transcriptional signature of fatigue derived from patients with primary Sjögren's Syndrome
Fatigue is a debilitating condition with a significant impact on patients’ quality of life. Fatigue is frequently reported by patients suffering from primary Sjo ̈gren’s Syndrome (pSS), a chronic autoimmune condition characterised by dryness of the eyes and the mouth. However, although fatigue ...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-66795 | biostudies-arrayexpress
UnknownHIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell Renal Cell Carcinoma.
Not available
S-EPMC11092754 | biostudies-literature
UnknownMicroenvironment-derived factors driving metastatic plasticity in melanoma.
Not available
S-EPMC5309794 | biostudies-literature
TranscriptomicsRNA-sequencing of human salivary gland from Sjogren's syndrome and sicca patients
The study aims to investigate the relevance of NKp30 receptor in the salivary glands inflammation of Sjogren’s syndrome patients in comparison to sicca patients (control group) analysing the transcriptomic profile of salivary gland tissues.
ORGANISM(S): Homo sapiens 
2021-09-13 | E-MTAB-10517 | biostudies-arrayexpress
UnknownChemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response.
Not available
S-EPMC12380605 | biostudies-literature
UnknownlncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Not available
S-EPMC6143179 | biostudies-literature
UnknownSetting minimum standards for training in EUS and ERCP: results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees.
Not available
S-EPMC6527477 | biostudies-literature
UnknownCompetence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography, From Training Through Independent Practice.
Not available
S-EPMC6504935 | biostudies-literature
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