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UnknownDetermination of the absolute oral bioavailability of niraparib by simultaneous administration of a 14C-microtracer and therapeutic dose in cancer patients.
Not available
S-EPMC5754411 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of estrogen receptor in human breast cancer cells (MCF-7) treated with estrogen
Cross talk between the Estrogen Receptor (ER) and ErbB2/HER-2 pathways have long been implicated in breast cancer aetiology and drug response1, yet no direct connection at a transcriptional level has been shown. We now show that estrogen-ER and tamoxifen-ER complexes directly repress ErbB2 transcrip...
ORGANISM(S): Homo sapiens 
2008-09-27 | E-TABM-563 | biostudies-arrayexpress
UnknownSurvival and prognostic factors in oligometastatic breast cancer.
Not available
S-EPMC9795523 | biostudies-literature
UnknownInfluence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review.
Not available
S-EPMC8545752 | biostudies-literature
UnknownFeatures on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.
Not available
S-EPMC9688812 | biostudies-literature
TranscriptomicsFoxA1 is a critical determinant of Estrogen Receptor function and endocrine response (part II)
Estrogen Receptor-a (ER) is the key feature in the majority of breast cancers and ER binding to the genome correlates with the Forkhead protein FOXA1 (HNF3a), but mechanistic insight is lacking. We now show that FOXA1 is the defining factor that governs differential ER-chromatin interactions. We sho...
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-25315 | biostudies-arrayexpress
TranscriptomicsFoxA1 is a critical determinant of Estrogen Receptor function and endocrine response (part I)
Estrogen Receptor-a (ER) is the key feature in the majority of breast cancers and ER binding to the genome correlates with the Forkhead protein FOXA1 (HNF3a), but mechanistic insight is lacking. We now show that FOXA1 is the defining factor that governs differential ER-chromatin interactions. We sho...
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-25314 | biostudies-arrayexpress
UnknownHuman mass balance study and metabolite profiling of 14C-niraparib, a novel poly(ADP-Ribose) polymerase (PARP)-1 and PARP-2 inhibitor, in patients with advanced cancer.
Not available
S-EPMC5694528 | biostudies-literature
UnknownVemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter study.
Not available
S-EPMC5603097 | biostudies-literature
UnknownPET imaging of GABA<sub>A</sub> receptors in pancreatic islets by [<sup>11</sup>C]flumazenil.
Not available
S-EPMC11612099 | biostudies-literature
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