Sort   by:  
 Page size 
UnknownArabidopsis Protein Repair L-Isoaspartyl Methyltransferases: Predominant Activities at Lethal Temperatures.
Not available
S-EPMC2980331 | biostudies-literature
GenomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs [ChIP-Seq]
The H2A variant H2AZ is essential for embryonic development and for proper execution of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions in H2AZ are likely key for its functional specialization, but we know little about how these differences contribute to chro...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40063 | biostudies-arrayexpress
TranscriptomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs [RNA-Seq]
The H2A variant H2AZ is essential for embryonic development and for proper execution of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions in H2AZ are likely key for its functional specialization, but we know little about how these differences contribute to chro...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40064 | biostudies-arrayexpress
GenomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40065 | biostudies-arrayexpress
GenomicsPRC2 coordinates lineage fidelity and DNA methylation during ESC differentiation (RRBS)
Polycomb Repressive Complex 2 (PRC2) catalyzes histone H3 lysine 27 tri-methylation, an epigenetic modification associated with gene repression. H3K27me3 is enriched at the promoters of a large cohort of developmental genes in embryonic stem cells (ESCs). Loss of H3K27me3 leads to a failure of ESCs ...
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-53507 | biostudies-arrayexpress
GenomicsH2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs [ChIP-seq]
Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in ESCs to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 mono-ubiquitylation (H2A.Z.1ub) by mutation of the PRC1 ...
ORGANISM(S): Mus musculus 
2016-01-21 | E-GEOD-53206 | biostudies-arrayexpress
TranscriptomicsPRC2 coordinates lineage fidelity and DNA methylation during ESC differentiation (RNA-Seq)
Polycomb Repressive Complex 2 (PRC2) catalyzes histone H3 lysine 27 tri-methylation, an epigenetic modification associated with gene repression. H3K27me3 is enriched at the promoters of a large cohort of developmental genes in embryonic stem cells (ESCs). Loss of H3K27me3 leads to a failure of ESCs ...
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-53506 | biostudies-arrayexpress
TranscriptomicsH2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs [RNA-seq]
Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in ESCs to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 mono-ubiquitylation (H2A.Z.1ub) by mutation of the PRC1 ...
ORGANISM(S): Mus musculus 
2016-01-21 | E-GEOD-53207 | biostudies-arrayexpress
GenomicsChange in H3K4me3 in Suz12(Bgal/Bgal) ESCs, and over Spinal Motor Neuron differentiation (ChIP-Seq)
Suz12(Bgal/Bgal) ESCs express a truncated form of Suz12 fused to Beta-galactosidase. These cells maintain a reduced level of H3K27me3 despite this mutation to a core component of PRC2, unlike Eed-/- ESCs whose H3K27me3 is ablated. This data shows the concomitant changes in H3K4me3 levels in these ce...
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-61248 | biostudies-arrayexpress
GenomicsPRC2 coordinates lineage fidelity and DNA methylation during ESC differentiation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-53508 | biostudies-arrayexpress
Sort   by:  
 Page size